CPG Hydrogel Research Program.

Hydrogels

Cambridge Polymer Group has an active hydrogel research program. We formulate new hydrogel compositions to meet mechanical, morphological, or surface property requirements, or modify existing hydrogel formulations. We have prepared multilayer hydrogel constructs, composite constructs, and custom cast hydrogels to mimic tissue and organs. Our analytical group are experts in characterizing the mechanical, chemical, and morphological nature of hydrogels, and can design custom tests for client-specific tasks. We also have several hydrogel formulations available for license. Our technology allows us to cast hydrogel constructs in a variety of shapes, with a range of specified mechanical properties.

Biomedical Research

Injectable Hydrogels for Nucleus Augmentation

CPG scientists have developed a formulation of hydrogel that can be injected as a liquid into the nuclear cavity of the spine to restore biomechanical function of a collapsed spinal unit. The liquid hydrogel will fully gel into a permanent hydrogel in vivo without chemical reaction or heat generation. Go to the presentations page for more information.

Injectable Hydrogels for Tissue Augmentation

CPG scientists have developed a formulation of hydrogel that can be used to reinforce human tissue, acting as a bulking agent. In collaboration with the Massachusetts General Hospital, this hydrogel has been used to treat animals showing mitral valve regurgitation. Additionally, CPG is investigating the use of this formulation for urinary incontinence and gastroesophageal reflux disease (GERD). The formulation can be injected through a long, narrow gauge catheter, and will gel up in vivo without a chemical reaction. Contact us for more information.

Synthetic Tissue

CPG is developing arterial analogs that mimick healthy and diseased blood vessels for product development, equipment validation and procedure training. We design custom tissue models based on client specifications, incorporating mechanical properties and geometry. Go to our application notes page for more information.