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Since its inception, CMOS image sensor (CIS) technology has held great potential to become the detector platform of choice for many scientific imaging applications. These demanding fields require a unique combination of sensitivity, speed, dynamic range, resolution, and field of view.
Although CIS technology has steadily improved it has not fully realized its potential, with CCD, and more recently EMCCD, detectors remaining the platforms of choice for the majority of high-end scientific imaging applications.
In this paper we present sCMOS, a breakthrough technology based on next-generation CIS design and fabrication techniques. sCMOS is poised for widespread recognition as a true scientific grade CIS, capable of out-performing most scientific imaging devices on the market today.
Unlike previous generations of CMOS and CCD-based sensors, sCMOS is uniquely capable of simultaneously offering:
• Extremely low noise
• Rapid frame rates
• Wide dynamic range
• High quantum efficiency (QE)
• High resolution
• Large field of view
Key applications for this new technology, already identified by PCO, Andor Technololgy, and Fairchild Imaging include:
Live cell microscopy - Particle Imaging Velocimetry (PIV) - Single Molecule Detection - Super resolution microscopy - Lucky astronomy/imaging - Adaptive optics - Solar astronomy - Luminescence - Fluorescence Spectroscopy - Bio-and Chemo-Luminescence - Genome sequencing (2nd and 3rd generation) - High content screening - Biochip reading - Photovoltaic inspection - X-ray tomography - Machine vision - TV/Broadcasting - Spectral (hyperspectral) imaging - TIRF - Spinning disk confocal microscopy - FRET - FRAP - Laser Induced Breakdown spectroscopy
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