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The Mark 95 is available with a hard or soft seat and a variety of diaphragm and o-ring materials, making the valve well-suited for virtually any sterile back pressure application.

The MK95 operates by sensing the inlet pressure, or back pressure, beneath the diaphragm, as flow enters from inlet port on the side. As the back pressure exceeds the setpoint, the diaphragm force compresses the range spring permitting the stem to move from the seat toward the open position. As the flow increases, the back pressure is relieved and the and spring and diaphragm relax, allowing the stem to return to the normally closed position. If a different set point is desired, a simple turn of the adjusting screw will increase or decrease the setting to any set point within the range covered by the regulator's spring.