Product Announcement from optek-Danulat, Inc.

Optical Density: Single Channel Absorption Probe.-Image

The model ASD25-N is a high precision, single channel absorption probe. This stainless steel probe is engineered for use in pilot or production scale fermenters or bioreactors. It precisely measures growth of microbial or cell cultures as a function of Near Infrared (NIR) absorption. The extremely durable ASD25-N probe is designed for sanitary bioprocess environments and can be used in CIP/SIP processes.


The ASD25-N uses light in the near infrared range (NIR) from 840 to 910 nm. A precisely defined, constant LED light beam penetrates the process medium. The attenuation of the light intensity, caused by absorption and/or scattering by dissolved and undissolved substances, is detected by a hermetically-sealed photo diode.


The ASD25-N probe is available with optical path lengths (OPL) of 1 mm, 5 mm, 10 mm or 20 mm. Shorter optical path length are typically used for dense cell cultures such as bacterial and yeast cultures. Longer OPLs are used for lower-absorbing mammalian cell cultures. The probe performs concentration measurements insensitive to color changes, since an optical filter adapts the wave length range.


The seal-less, sapphire optical window design eliminates crevices and gaps to assure the highest level of sterility, cleanability and sensor integrity. The surface of the wetted parts is electro-polished and may be specified to comply with BN2. The probe mounts conveniently through a standard 25 mm Ingold-type port.

ASD25 Features:

  • Inline real time process monitoring
  • Concentration measurement insensitive to color changes
  • Superior sapphire window with no seals, gaps or crevices
  • Extremely low maintenance
  • CIP/SIP-compatible
  • All wetted material and surface finishes are certifiable and traceable
  • Conforms to FDA requirements
  • Designed for cGMP facilities
 
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