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The Prominence UFLC System is up to 10 times faster than a conventional HPLC system that uses a 5-µm particle column. This performance is achieved while maintaining high-quality analytical results not possible on specialized systems that incorporate design concessions due to extreme pressure requirements. Key to the system is the SIL-20A autosampler, capable of a 10-second injection cycle while delivering <0.3 % RSD area repeatability. Prominence UFLC also successfully reduces carryover by inhibiting the adsorption of samples through precise engineering and the prudent choice of wetted materials in the flow path. The durability of the injection mechanism is evident from 100,000 cycle tests showing no degradation in performance.

With Shim-pack XR Series columns, Prominence UFLC can provide high-speed, high-resolution analysis at pressures below 30 MPa (300 kgf/cm²). The columns are available with inner diameters of 2, 3 or 4.6 mm and lengths of 30, 50, 75 or 100 mm, allowing FAST LC to be performed on conventional HPLC equipment.

With its micro-plunger design, the LC-20AD solvent-delivery system provides unmatched gradient resolution and reproducibility, and has a delivery range of 100 nL/min to 10 mL/min. Prominence UFLC is versatile and can accept an assortment of flow-control valves and a column-switching system, allowing it to be used for many other applications, such as two-dimensional HPLC or micro to semi-micro analysis.

"Prominence UFLC is not just about faster performance," said Curtis R. Campbell, PhD, HPLC Product Manager. "It raises total system productivity to new levels by generating accurate, repeatable results and by offering users the flexibility to perform several analytical tasks with one piece of high-performance equipment. The Prominence UFLC System is all about generating high-quality, reproducible data."

When presented with a unique challenge that demands the use of longer columns for extra resolution, users can convert their current Prominence UFLC to a Prominence UFLCXR system, which is capable of system pressures up to 9500 psi (66MPa). Unlike many high-pressure systems, the system delivers data with high integrity and reproducibility, a result of fully re-engineered components in the injection valve. Together, they represent the ultimate solution for ultra-fast analysis.