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  • Basics of Design Engineering: Hydraulics New Sealing Systems Take the Heat
    materials are only capable of 90 C continuous system temperatures (CST), with select blends reaching 100 C For instance, top-of-the-line sealing systems often include a buffer seal, asymmetrical rod seal, and vented rod wiper. Our baseline systems use 100 C CST urethane seals (Material
  • Medical Device Link .
    Cliniqa (Fallbrook, CA) offers trilevel hsCRP and 14 constituent tumor marker controls. Biochemicals and chemical reagents encompass a very broad array of materials that are the fundamental elements of IVD products. Antibodies, enzymes and other proteins, nucleic acids, buffer compounds, various
  • Guided Wave Radar at Genentech: A Novel Technique for Non-invasive Volume Measurement in Disposable Bioprocess Bags
    By Bryan Bean, Tim Matthews, Neria Daniel, Steve Ward, Brad Wolk, Genentech, Inc. Disposable bioprocess bags are increasingly being used in biopharmaceutical operations for buffer storage, buffer and media prep, bioreactors, product pooling and storage of bulk drug substance. Disposables offer
  • Application Note: Blood Alcohol Analysis (.pdf)
    methods to eliminate the chance for operator error. * A logging feature in the software to record all pump operations. * Small volume accuracy to reduce wasted buffer associated with volumetric glassware
  • Blend Controls Boost Liquid Chromatography Performance
    . Such variability is a key contributor to many pharmaceutical companies' need for a "hidden factory, " or an extensive non-value-adding infrastructure, to ensure product quality and safety (Figure 1). Chromatography process variability starts with buffer or solution make-up; effects of that variability ripple
  • Selection Factors for Seals
    this hazard. For systems with external circulation, pressure drops can be detected with a pressure-sensitive switch. is the bane of face seals. Faces should be cleaned before initial start-up to prevent premature failures. With liquids that form abrasives on contact with air, a buffer zone or quench gland
  • Chromatography Roundup
    . The smaller sorbent volume means 95% less buffer consumption, and thus cost savings. As with other disposables, Sartobind SingleSep Q capsules are disposable and carry no cleaning validation or initial hardware costs, says Mora. (Kyoto, Japan) HPLC production-scale chromatography products in the U.S.
  • Medical Device Link . Blocking strategies for nylon membranes used in enzyme-linked immunosorbent assays
    a membrane is compressed against an absorbent pad and solutions are delivered to the top face of the membrane. The primary antibody is bound to the surface of the membrane, which is then blocked to prevent nonspecific binding. The analyte is presented in a test solution, which can be either a buffer

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