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  • A Wave, Suspended: Follow-on Biologics
    procedures established for small molecules, human growth hormone, insulin, interleukins and interferons are available, as are versions of therapeutic proteins modified with polyethylene glycol (PEG) residues to improve pharmacokinetics.
  • New wound-healing materials on the horizon
    III to a synthetic material called polyethylene glycol. Mixing solutions of this peptide-polyethylene glycol combination with heparin instantly produces a three-dimensional matrix. "It's a very rapid assembly and the matrix can take any shape, " says Panitch, who specializes in regenerative medicine
  • Medical Device Link . FACTORS IN SELECTING MEDICAL SILICONES
    is a four-part evaluation involving animal (mouse and rabbit) testing of extracts of saline, vegetable oil, alcohol, and polyethylene glycol along with a 5-day rabbit intramuscular implantation test. While this level of testing is widely used and accepted in the medical products business, the significance of the
  • A Wave, Suspended: Follow-on Biologics
    procedures established for small molecules, human growth hormone, insulin, interleukins and interferons are available, as are versions of therapeutic proteins modified with polyethylene glycol (PEG) residues to improve pharmacokinetics. Part of the challenge that FDA faces is the sheer complexity
  • Controlled Release Moves Beyond Patent Extension
    . Mechanical prolongation of drug release, although thus far dominating CR markets, is not the only strategy. Conjugation with polyethylene glycol (PEG; PEGylation ) has created immense value for developers of protein drugs. When attached to proteins or peptides, highly water-soluble PEG polymer
  • Drug Delivery: The "Great Equalizer "
    ,? Haley observes. Perhaps the most prominent, technologically compelling example is PEGylation of proteins and peptides as practiced by Nektar Therapeutics (San Carlos, Calif.). Through PEGylation, polyethylene glycol residues are chemically attached to peptides and proteins to improve
  • Characterization of the volatile profile of Brazilian Merlot wines through
    and optimal conditions. were: a polar (polyethylene glycol)/medium polar (50% phenyl 50% dimethyl arylene siloxane). column set, oven temperature offset of 10 ?C, 7 s as modulation period and 1.4 s of hot pulse duration. Co-elutions came up to 138 compounds in 1D and some of them were resolved in 2D
  • Shims? Make mine laminated!
    material made of glycol polyethylene terephthalate film. It is the lightest and lowest-cost material listed. It's often quicker and less expensive to use a shim, a thin piece of metal or composite, to level a machine tool or make components fit together than grinding and machining to make the same

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