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  • CD Detection of Myoglobin Structure During an Automated pH Titration
    (denatured) by heating, changing the pH, and adding reagents such as detergents, urea, or guanidine hydrochloride. Myoglobin is a common model protein used to investigate the structural changes that can occur upon pH titration. Myoglobin is an extremely compact heme protein (MW ~ 17,800), found primarily
  • Concentration Measurement
    by. more that one concentration test method. Each concentration method measures a specific chemical, group. of chemicals or fluid characteristic. Typical concentration measurements are: Total Alkalinity (TA). BCG Titration (BCG). Refractometer. CIMCHEK (R) Test Strips. Total alkalinity is a pH based
  • Avoiding Machinery Wear and Corrosion
    . When moisture is present on a metal surface, an oxidative chemical reaction can take place. Like all chemical reactions, temperature increases expedite the process, causing premature wear. Water content of lubricating oils has typically been measured by performing a Karl Fischer titration. While
  • Determination of Water Hardness
    Originally the hardness of water was defined as the capacity of water for destroying the lather of soap. The hardness was determined by a titration with a standard soap solution. Metal ions including have the ability to cause hardness. However, today water hardness means the total calcium
  • Water Activity as an Alternative to Karl Fischer Moisture Testing (.pdf)
    Water has long been recognized as important in determining product safety and stability. Karl Fischer titration is a widely used analytical method for quantifying water content in a variety of pharmaceutical products. Simply knowing the total amount of water by Karl Fischer may not be the most
  • Method for Computing Alkalinity Based On Total Inorganic Carbon (TIC) and Related Data (.pdf)
    Standard Methods (Ref. 1) has a procedure using nomographs for estimating CO2 concentrations (Method 4500-CO2 B) based on total alkalinity titrations. The method presented here reverses that process by computing alkalinity based on TIC measurements using infrared technology. These two methods
  • Phosphoric Acid Concentration
    The use of phosphoric acid solutions is common in the semiconductor industry to both clean and etch metal surfaces. The concentration of the phosphoric acid is important to optimize these processes. Typically the laboratory method used for this determination involves one or more titrations
  • Therapeutic Dose: Avoiding "Cool Hand Luke " Syndrome: Part II
    chemistry within the broader framework of chemistry. For those people, it s "pharma versus everyone else. " For example, years ago, when I worked at a surfactant company, I remember that we had once had to run a simple two-layer titration method for sodium lauryl sulfate (SLS or sodium dodecyl

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