Trial facility leasing provides contractual access to trial facility, so that customers can evaluate or prove processes or process equipment before making major capital expenditures. Facilities may be on-site or in-house. Contracts typically include rental fees, lease terms, transportation costs, cleaning, etc.
Other specialized, proprietary or unlisted processing services.
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Acylation synthesis produces deactivated monoacylates through an electrophilic, aromatic substitution reaction between arenes and acyl chlorides or anhydrides. In the Friedel-Crafts alkylation processes, the electrophilic aromatic substitution is catalyzed by a Lewis-acid and produces alkylated products through the reaction of arenes with alkyl halides or alkenes. Alkyl groups can activate arene, resulting in polyalkylated products. Typically, Friedel-Crafts reactions for alkylation or acylation of aromatic compounds are catalyzed by aluminum chloride or other Lewis acids.
Compounding mixes or blends and/or reacts all of the ingredients required to produce a finished product. For example, a compounded plastic resin or elastomer compound typically consists of base polymer resin(s), chemical additives, and reinforcing or extending fillers. Compounding can be used for plastics, rubber, elastomers, cleaning agents, lubricants, greases, masterbatch colorants (pigments, dyes), additive masterbatches, organic chemicals, chemical additives, metal working fluids, oils, oil and fuel additives, fuel mixtures, and other materials.
Crystallization cools a liquid solution or evaporates a solvent in order to form solid, solute crystals. As they leave the crystallizer, the slurry crystals are often forced through a circulation evaporator and may subsequently be separated from the liquid in a filter or centrifuge.
Distillation applies and removes heat in order to separate a liquid or vapor mixture of two or more substances into component fractions of a desired purity. Chemicals and conditions determine which distillation processes can be used. Examples include no-pressure distillation, vacuum distillation, steam distillation, molecular distillation, and thin film distillation.
Drying uses evaporation, sublimation, or freeze-drying processes to remove liquids or moisture from bulk solids, powders, parts, continuous sheets or other liquids.
In the Fischer-Speier esterification method, esterification of acids occurs by refluxing with excess alcohol in the presence of hydrogen chloride or other acid catalysts.
Fermentation is used in the production of drugs, foodstuffs and beverages. The process uses fermentation, biological catalysts or enzymatic compounds, microrganisms, and other biological agents or biotransformations to process or synthesize products. Enzymes are very effective at breaking down certain proteins. Composting is a biotransformation process that uses bacteria to break down organic waste.
Molecular sieve filtration often uses a porous molecular structure that selectively adsorbs or rejects molecules based on differences in molecular size or shape.
Granulation, pelletization, briquetting or agglomerations are size enlargement processes. Granulation or agglomeration increases particle size by adhering or bonding together several fine particles with a liquid or wax binder to from larger agglomerates. Pelletization or briquetting compacts fine powders into larger pellets or briquettes.
Halogenation is the reaction, chemical combination or exposure of water or other chemicals to fluorine, chlorine, bromine, iodine or other halogens. Exposing water to chlorine can destroy biological contaminants. Halogenation processes include fluorination, chlorination, bromination, electrolytic fluorination and iodination as well as related processes such as iodine recovery.
Hydroformylation or formylation reactions such as Duff, Gattermann-Koch or Vilsmeier-Haack are performed. In Duff reactions, the formylation of phenols or aromatic amines with hexamethylenetetramine uses an acidic catalyst. Gattermann-Koch reactions are catalyzed by using aluminum chloride at high-pressure in order to achieve the formylation of benzene, alkylbenzenes or polycyclic aromatic hydrocarbons with carbon monoxide and hydrogen chloride. Formylation of the amino acids in proteins is a naturally occurring process.
Hydrogenation is the reaction of hydrogen with another chemical or raw material. For example, Sorbital is formed through the hydrogenation of corn syrup. Formylation of the amino acids in proteins is a naturally occurring process.
Fischer Tropsch (gas to liquids) or linear alpha olefin hydroformylation processes are used in the production of synthetic oils fluids. In the Fischer Tropsch reaction or Synthol process, hydrocarbons, aliphatic alcohols, aldehydes, and ketones are synthesized by the catalytic hydrogenation of carbon monoxide using synthesis gas enriched from the passage of steam over heated coke.
The Bergius reaction is used to synthesize petroleum-like hydrocarbons by the hydrogenation of coal at high temperatures and pressures (~ 450°C @ 300 atm) with or without catalysts.
Milling, ball milling, crushing, shredding, granulating, pulverizing, or other services are offered in order to reduce coarse, bulk solids into finer granules or powders.
Processing or expertise in using organometallic or Grignard reactions is available. Originally, Grignard reactions were the addition of organomagnesium compounds or Grignard reagents to carbonyl compounds to generate alcohols. The reaction scope now includes the addition of Grignard reagents to a wide variety of electrophilic substrates.
Packaging is used for chemicals, pharmaceuticals or bulk materials such as powders, granules, liquids or continuous webs. Alternatively, packaging also provides encapsulation, microencapsulation, tableting, blister packaging or drug delivery systems for powdered or liquid drugs, vitamins or other substances.
Sterilization or disinfecting of chemicals, materials, surfaces or environmental media (water, soil, etc.) kills or destroys any microbial contamination (mold, bacteria, viruses, protozoa, etc.).
Treatment or decontamination of liquids, oils, colloids, dispersions, water, soil, building materials, waste, scrap, powders, granules or other bulk materials.
Ultraviolet (UV) light exposure is used to degrade, breakdown, sterilize certain compounds or chemicals. UV light or radiation sources are used to initiate reactions or cure certain polymers and resins.
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Facilities locate sterilization and/or manufacturing equipment in a clean room in order to eliminate or minimize the contamination of processed materials, chemicals or products.
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Processing, reacting, extracting or synthesizing of biochemicals such as proteins, peptides, amino acids, amino acid analogs, DNA, RNA, steroids, carbohydrates, oligonucleotides, lipids, animal fats, vegetable oils, waxes, sterols, triglycerides, other biological or botanical derivatives, active pharmaceutical ingredients (APIs) or high potency actives (HPAs).
Processing or producing of cleaning and surface active agents such as cleaners, detergents, surfactants, emulsifiers, flocculants, dispersing agents, settling agents, and soaps (saponification end products).
Fluid processing systems are to process cosmetics such as algae extracts, bee’s wax, brown moss extracts, flower extracts, lanolin alcohols, root extracts, wool fatty acids, wool alcohols, and volatile oils and scents.
Synthesizing or processing of foods and beverages such as aroma concentrates, butter, capsicum, coffee, cacao biocatalyst concentrates, diglycerides, dimeric fatty acids, fatty acids and derivatives, fish oils, fruit juices, milk products, mono-glycerides, palm oils, protein and protein substances, rice bran oils, soybean oil, seed oils, sugar derivatives, tea, and tocopherols.
Synthesizing or processing of pharmaceuticals or drugs, a category that includes vitamins, amino-acid esters, antibiotics, beta-carotene, ferments, glucose derivatives, hormones, antioxidants, and indoles.
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Cobalt and cobalt alloys are non-ferrous magnetic alloys with high strength and toughness, excellent corrosion and oxidation resistance, and high temperature strength. Cobalt can also be magnetized. Cobalt's properties result in the use of cobalt alloys in jet engine super-alloy components, prosthetic devices, magnets, and cutting tool binders. Cobalt is a useful alloying element in tool, maraging and other alloy steels.
Noble and precious metal alloys such as silver, gold, platinum and palladium alloys are extremely resistance to corrosion and oxidation. Noble and precious metal alloys are used in electrical contacts, electronic connectors, chemical process components, catalysts, jewelry and other specialized applications.
Stainless steels are highly corrosion resistant, ferrous alloys that contain chromium and/or nickel additions. There are three basic types of products: austenitic stainless steels, ferritic and martensitic stainless steels, and specialty stainless steels and iron superalloys.
Austenitic stainless steels (AISI 300 / 200 Series) are highly corrosion resistant, ferrous alloys that contain chromium and nickel or manganese additions. Generally, austenitic stainless steels are more corrosion resistant than ferritic or martensitic stainless steels. Annealed austenitic stainless steels are non-magnetic. Cold working is used to harden austenitic stainless steels because these alloys do not respond to conventional quench and temper hardening processes.
Ferritic and martensitic stainless steels are highly corrosion resistant, ferrous alloys that contain chromium and/or carbon additions. Ferritic stainless steels are soft, easy to form metal alloys. Cold working is used to harden ferritic stainless steels because these alloys do not respond to conventional quench and temper hardening processes. Ferritic stainless steels are formed to fabricate mufflers and other sheet metal components that require good corrosion resistance. Martensitic stainless steels can be hardened by a conventional quench and temper operation. Martensitic stainless steels are used for knife blades, tooling or other applications that require good corrosion resistance combined with higher hardness and wear resistance.
Specialty stainless steels and iron superalloys are highly corrosion resistant, ferrous alloys containing chromium, nickel or other alloying additions to provide high strength or heat resistance. Duplex and precipitation hardening stainless steels belong in this category.
Titanium and titanium alloys are non-ferrous metals with excellent corrosion resistance, good fatigue properties, and a high strength-to-weight ratio. Titanium's properties result in the use of titanium and titanium alloys in aircraft or air frame parts, jet engine super-alloy components, corrosion resistant chemical process equipment (valves, piping, and pumps), prostheses or medical devices, and marine equipment.
Other unlisted, specialty or proprietary metals or alloy grades. These materials are based on a unique composition or alloy system, use a novel processing technology, or have properties designed for specific applications.
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Typically, laboratory or benchtop scale means that processing capacity does not exceed a few pounds or a few gallons. Actual quantities vary based on the type of material. For example, laboratory scale quantities may be expressed in milligrams for nanomaterials and specialized biochemical compounds. Usually, one person can easily and safely operate laboratory scale equipment. This category excludes facilities whose function is to produce commercial quantities.
Pilot scale is a small-scale production process that is larger than laboratory scale and used to develop a subsequent full-scale process. Typically, pilot scale quantities are in the range of several drums (e.g., 55-gallon drums) or hundreds of pounds or gallons; however, quantities vary with the density and type of processed material, chemical or product. Pilot scale facilities are better than laboratory scale facilities at simulating production processes and can be used for troubleshooting, improving and optimizing processes.
Companies may have commercial, production, field or industrial scale processing facilities. Typically, the processing ranges are in thousands of gallons or pounds; however, quantities vary by material, chemical, or product.
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AS 9001 is a set of quality guidelines and requirements published by the Society of Automotive Engineers (SAE) in cooperation with major aerospace manufacturers. AS 9001 is based on ISO 9001 but maintains a particular focus on the aerospace industry.
Supplier is permitted by the U.S. Department of Transportation to ship or transport specific class (solid, hazardous, medical, etc.) waste or scrap materials.
Supplier is permitted by the EPA for specific recycling or reclamation activities or processes wasters in full compliance with standards, guidelines and methods set forth by the Environmental Protection Agency (EPA).
Companies comply with International Standards Organization (ISO) standards. Examples include ISO 7779, ISO 9000, ISO 9001, ISO 9002, ISO 13485, ISO 14000 and ISO 17025. ISO 7779 covers acoustics and the measurement of airborne noise emitted by information technology (IT) and telecommunications equipment. ISO 9000 establishes standards for quality management. ISO 9002, a certification that has been superseded by ISO 9001:2000, is dedicated to continuous improvement. ISO 13485 covers medical devices, quality management systems and requirements for regulatory purposes. ISO 14000 establishes standards for environmental management, a term that describes a company’s efforts to minimize its harmful effects on the environment and improve its environmental performance. ISO 17025 outlines general requirements for the competence of testing and calibration laboratories.
ISO 9001:2000 establishes requirements for company quality management systems. Standards range from manufacturing to services such as design, development, production, and installation.
ISO 14000 provides an internationally recognized framework for environmental management, measurement, evaluation and auditing. It does not prescribe environmental performance targets, but instead provides organizations with tools for assessing and controlling the impact of activities, products or services on the environment. These standards are designed to be flexible enough to be used by any organization of any size and in any field. They address the following subjects: environmental management systems, environmental auditing, environmental labels and declarations, environmental performance evaluation, and life cycle assessment.
Other unlisted, specialized, or proprietary certification or standard.
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Companies are located in the Northeast United States, namely Connecticut, Maine, Massachusetts, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island and Vermont.
Companies are located in the Southern United States, namely Alabama, Arkansas, Delaware, Florida, Georgia, Kentucky, Louisiana, Maryland, Mississippi, Missouri, North Carolina, Oklahoma, South Carolina, Tennessee, Texas, Virginia, Washington D.C., and West Virginia.
Companies are located in the Midwest United States, namely Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Nebraska, North Dakota, Ohio, South Dakota and Wisconsin.
Companies have facilities in South American countries such as Argentina, Brazil, or Chile; or in Central American countries such as Costa Rica, Honduras, Panama, etc.
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