BioMedical Engineering OnLine

The latest news from BioMedical Engineering OnLine
Evaluation of an open access software for calculating glucose variability parameters of a continuous glucose monitoring system applied at pediatric intensive ca...
Source, April 24, 2015
Background: Continuous Glucose Monitoring (CGM) has become an increasingly investigated tool, especially with regards to monitoring of diabetic and critical care patients. The continuous glucose data allows the calculation of several glucose variability parameters, however, without specific applicat...
Model demonstrates functional purpose of the nasal cycle
Source, April 24, 2015
Background: Despite the occurrence of the nasal cycle being well documented, the functional purpose of this phenomenon is not well understood. This investigation seeks to better understand the physiological objective of the nasal cycle in terms of airway health through the use of a computational nas...
Wound perimeter, area, and volume measurement based on laser 3D and color acquisition
Source, April 24, 2015
Background: Wound measuring serves medical personnel as a tool to assess the effectiveness of a therapy and predict its outcome. Clinically used methods vary from measuring using rules and calipers to sophisticated methods, based on 3D measuring. Our method combines the added value of 3D measuring a...
A lab-on-a-chip for hypoxic patch clamp measurements combined with optical tweezers and spectroscopy- first investigations of single biological cells
Source, April 20, 2015
The response and the reaction of the brain system to hypoxia is a vital research subject that requires special instrumentation. With this research subject in focus, a new multifunctional lab-on-a-chip (LOC) system with control over the oxygen content for studies on biological cells was developed. Th...
Identifying typical physical activity on smartphone with varying positions and orientations
Source, April 17, 2015
Background: Traditional activity recognition solutions are not widely applicable due to a high cost and inconvenience to use with numerous sensors. This paper aims to automatically recognize physical activity with the help of the built-in sensors of the widespread smartphone without any limitation o...
Porous deproteinized bovine bone scaffold with three-dimensional localized drug delivery system using chitosan microspheres
Source, April 17, 2015
Background: Bone substation grafts, such as hydroxyapatite (HA) and tricalciumphosphate (TCP), have been extensively used in clinical applications, but evidence suggests that they offer poor osteoinductive properties compared to allografts and autografts. In order to increase bone growth with such g...
Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models
Source, April 17, 2015
Background: The management and prognosis of aortic dissection (AD) is often challenging and the use of personalised computational models is being explored as a tool to improve clinical outcome. Including vessel wall motion in such simulations can provide more realistic and potentially accurate resul...
Three-dimensional cardiac computational modelling: methods, features and applications
Source, April 17, 2015
The combination of computational models and biophysical simulations can help to interpret an array of experimental data and contribute to the understanding, diagnosis and treatment of complex diseases such as cardiac arrhythmias. For this reason, three-dimensional (3D) cardiac computational modellin...
Selection of suitable hand gestures for reliable myoelectric human computer interface
Source, April 11, 2015
Background: Myoelectric controlled prosthetic hand requires machine based identification of hand gestures using surface electromyogram (sEMG) recorded from the forearm muscles. This study has observed that a sub-set of the hand gestures have to be selected for an accurate automated hand gesture reco...
Visco-hyperelastic constitutive modeling of soft tissues based on short and long-term internal variables
Source, March 30, 2015
Background: Differential-type and integral-type formulations are two common approaches in modeling viscoelastic materials. A differential-type theory is often derived from a Helmholtz free energy function and is usually more suitable for the prediction of strain-rate dependent mechanical behavior du...
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