BioMedical Engineering OnLine

The latest news from BioMedical Engineering OnLine
The necessity of identifying the basal glucose set-point in the IVGTT for patients with Type 2 Diabetes
Source, 9 hours ago
Background: The model-based dynamic insulin sensitivity and secretion test (DISST) uses fasting glucose (G 0 ) as the basal glucose (G B ) concentration when assessing insulin sensitivity (SI). However, this model was developed in a healthy, normoglycaemic cohort. We sought to determine the suitabil...
Modelling endogenous insulin concentration in type 2 diabetes during closed-loop insulin delivery
Source, 9 hours ago
Background: Closed-loop insulin delivery is an emerging treatment for type 1 diabetes (T1D) evaluated clinically and using computer simulations during pre-clinical testing. Efforts to make closed-loop systems available to people with type 2 diabetes (T2D) calls for the development of a new type of s...
Lung segmentation on standard and mobile chest radiographs using oriented Gaussian derivatives filter
Source, 9 hours ago
Background: Unsupervised lung segmentation method is one of the mandatory processes in order to develop a Content Based Medical Image Retrieval System (CBMIRS) of CXR. The purpose of the study is to present a robust solution for lung segmentation of standard and mobile chest radiographs using fully ...
A flexible and low power telemetric sensing and monitoring system for chronic wound diagnostics
Source, February 28, 2015
Background: Non-healing chronic wounds, such as venous leg ulcers, can be monitored non-invasively by using modern sensing devices and wireless technologies. The development of such a wireless diagnostic tool may improve chronic wound management by providing evidence on efficacy of treatments being ...
Unified frame of reference improves inter-subject variability of seismocardiograms
Source, February 25, 2015
Background: Seismocardiography is the noninvasive measurement of cardiac vibrations transmitted to the chest wall by the heart during its movement. While most applications for seismocardiography are based on unidirectional acceleration measurement, several studies have highlighted the importance of ...
Differential sequential patterns supporting insulin therapy of new-onset type 1 diabetes
Source, February 21, 2015
Background: In spite of numerous research efforts on supporting the therapy of diabetes mellitus, the subject still involves challenges and creates active interest among researchers. In this paper, a decision support tool is presented for setting insulin therapy in new-onset type 1 diabetes. Methods...
Biomechanical evaluation of a novel wheelchair backrest for elderly people
Source, February 21, 2015
Background: Back pain is a common complication of wheelchair-bound elderly people. Seating system is a key factor that influences spinal curvature, back muscle activation, interface pressure, and comfortability. A seating system can maintain lumbar lordosis, lower back muscle activity, and decrease ...
Iterative multi-channel radio frequency pulse calibration with improving B 1 field uniformity in high field MRI
Source, February 21, 2015
Background: In high field MRI capable of multi-channel radio frequency (RF) transmission, B 1 shimming is a time-consuming job because conventional B 1 shimming techniques require B 1 mapping for each channel. After acquiring the complex-numbered B 1 field maps, the optimal amplitude and phase of th...
Segmentation of MR image using local and global region based geodesic model
Source, February 18, 2015
Background: Segmentation of the magnetic resonance (MR) images is fundamentally important in medical image analysis. Intensity inhomogeneity due to the unknown noise and weak boundary makes it a difficult problem.MethodThe paper presents a novel level set geodesic model which integrates the local an...
Simulation and evaluation of freeze-thaw cryoablation scenarios for the treatment of cardiac arrhythmias
Source, February 17, 2015
Background: Cardiac cryoablation is a minimally invasive procedure to treat cardiac arrhythmias by cooling cardiac tissues responsible for the cardiac arrhythmia to freezing temperatures. Although cardiac cryoablation offers a gentler treatment than radiofrequency ablation, longer interventions and ...
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