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Active Pharmaceutical Hydrogenation

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  • IFPAC Conference Highlights Pharmaceutical Applications of PAT
    use of NIR as well as infrared (IR) and reduction-oxidation techniques. ADVERTISEMENT. "New PAT strategies are being implemented into API [active pharmaceutical ingredient] facilities for controlling and monitoring of process chemical reactions and hydrogenations," she said. "Reactions no longer...
  • New Methods for the PAT Toolbox
    . Kaiser Optical's experience with Raman cuts across pharmaceutical processes, for example, to perform polymorph screening, or to monitor catalytic hydrogenation and Grignard reactions, crystallization, and general reactions. Bruker Optics (Billerica, Mass.) has a similar story. It had been active...
  • Less is More in API Process Development
    the product? Inside USP s New Pharmaceutical Ingredient Verification Program Is IT a Catalyst for India s Drug Industry Growth? Aptuit Acquires Evotec AG's API Business Pfizer CentreSource and ScinoPharm Taiwan to Manufacture Steroid Active Pharmaceutical Ingredients Alpharma Sells API Business to 3i...
  • Less is More in API Process Development
    the product? Inside USP s New Pharmaceutical Ingredient Verification Program Is IT a Catalyst for India s Drug Industry Growth? Aptuit Acquires Evotec AG's API Business Pfizer CentreSource and ScinoPharm Taiwan to Manufacture Steroid Active Pharmaceutical Ingredients Alpharma Sells API Business to 3i...
  • Less is More in API Process Development
    and industrially advantageous one-pot process for the preparation of alkyl 3-cyclopropyl amino-2-[2,4-dibromo-3-(difluoromethoxy) benzoyl]-2-propenoates of in which R represents methyl or ethyl, which are valuable intermediates for the production of highly active antibacterial quinolone medicaments...
  • Pilot Plant Partnerships
    are reasonable; those that can only be solved by every employee working double shifts for a month are unmanageable. Regulatory Hurdles Hiring a contract manufacturer without relevant regulatory experience would be unthinkable, but also look for an active dialogue between manufacturing and quality assurance...
  • Going Small, Thinking Big
    1 | 2 | 3 Next >> View on one page By Paul Thomas, Managing Editor Plenty of drug makers today are thinking small. Real small. In the neverending pursuit of a better route to certain intermediates and active pharmaceutical ingredients (APIs) and more streamlined operations, drug companies...
  • Using Raman to Track API and Solid Dosage Forms During Drug Development
    This quick, one-time registration gives you access to members-only site benefits. Many pharmaceutical quality programs fail to account for the fact that API forms can change during drug development. They may be the same compound, chemically, but have different particle sizes or morphologies...
  • Drug Development Through the Looking Glass
    , Netherlands, Linz, Austria and South Haven, Mich.) and a kilogram shop in Regensburg, Germany. All produce active pharmaceutical ingredients and advanced or registered intermediates. Less-advanced starting materials are sourced from partner companies in India and China, and new technology...
  • About Propylene Glycols
    of its low human toxicity and. desirable formulation properties it has been an important ingredient for years in food, cosmetic, and pharmaceutical. products. Manufacturing. Wurtz (2) first prepared propylene glycol in 1859 by hydrolysis of propylene glycol diacetate, and it was commercialized...

Engineering Web Search: Active Pharmaceutical Hydrogenation

Hydrogenation - Wikipedia, the free encyclopedia
An illustrative example of a hydrogenation reaction is the addition of hydrogen to maleic acid to form succinic acid.[2 Numerous important
Adsorption - Wikipedia, the free encyclopedia
Lesser known, are the pharmaceutical industry applications as a means to prolong neurological exposure to specific drugs or parts thereof.
Chemical & Engineering News: Cover Story - CHIRAL...
are key in the selectivity of BrXuPhos, a new ruthenium asymmetric hydrogenation catalyst with 1,2-diamino-1,2-diphenylethane and
See Chemical & Engineering News Information
Chemical & Engineering News: Cover Story - REMOVING...
what they call ?the art of meeting palladium specifications? in active pharmaceutical ingredients (APIs), describing four possible attacks:
See Chemical & Engineering News Information
2006 Greener Synthetic Pathways Award | Green Chemistry | US...
Novel Green Synthesis for ?-Amino Acids Produces the Active Ingredient in Januvia?
2010 Greener Reaction Conditions Award | Green Chemistry | US...
have developed a second-generation green synthesis of sitagliptin, the active ingredient in JanuviaTM, a treatment for type 2 diabetes.
See Green Chemistry Program, U.S. EPA Information
Carbon-coated structured supports. Preparation and use for...
Preparation and use for nitrobenzene hydrogenation Authors: Philippe Rodriguez, Florica Simescu-Lazar, Val??rie Meille, Thierno Bah, St??phanie
New twists on catalysis
Chemists around the world have discovered several new twists to improve the performance of asymmetric catalysts in hydrogenation reactions.
See Royal Society of Chemistry Information
Hot Articles
US scientists report a safe way to perform large-scale palladium-catalysed oxidations for pharmaceutical synthesis.
Hallochem Pharma Co., Ltd-ÖØÇìºÆ¿µÒ½Ò©»¯¹¤ÓÐÏÞ¹«Ë¾
with some famous pharmaceutical collegesand research institutes in China and abroad.Currently we specialize in active pharmaceutical ingredients

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