Alcohol Validation

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• Products & Services
  MPE Group USA, Jongia Div. Nonchemical Sterilization Process for Nonwovens E-Beam offers a non-chemical process for the bioreduction and sterilization of nonwovens, permitting manufacturers and packagers to assure product integrity without the use of alcohol or chemical additives. The process...
• Improving Control of the Extrusion Spheronization Process
  . The physical properties of two types of commercial MCC showed differences during the step of moistening, thereby affecting the particle size and hardness of the pellets obtained The most commonly used granulating liquid is water, although in some cases the use of alcohol or a water-alcohol mixture...
• MICRO: Wet Surface Technologies
  an isopropyl alcohol (IPA) vapor condensation drying technology. Another significant feature of the tool is its use of three megasonic transducers. This article describes the system and presents performance data that demonstrate its capabilities in a variety of applications. Figure 1 shows a schematic...
• Guided Wave Radar at Genentech: A Novel Technique for Non-invasive Volume Measurement in Disposable Bioprocess Bags
  By Bryan Bean, Tim Matthews, Neria Daniel, Steve Ward, Brad Wolk, Genentech, Inc. Stedim-40 is a 200 +/- 25-um thick film constructed from the co-extrusion of seven layers, including ultra-low density polyethylene (fluid contact layer), ethyl vinyl alcohol, polyamide, polyethylene terephthalate...
• Guided Wave Radar at Genentech: A Novel Technique for Non-invasive Volume Measurement in Disposable Bioprocess Bags
  : A 500-L gamma-irradiated Sartorius-Stedim Flexel 3-D bag with Stedim-40 film was installed in the 500-L bioprocess container. Stedim-40 is a 200 +/- 25-um thick film constructed from the co-extrusion of seven layers, including ultra-low density polyethylene (fluid contact layer), ethyl vinyl alcohol...
• Purdue Pharma Blazes a Trail for Drug Security Purdue Ceases Palladone Manufacturing Citing safety concerns, FDA has forced the drug off the market By Gregg Carlstrom Purdue Pharma L.P. is halting production of its prescription painkiller Palladone,
  regarding alcohol-related dangers — that alcohol could accelerate the rate of release of the drug’s active ingredient, hydromorphone — when seeking regulatory approval for Palladone last winter. The drug’s label carries a warning advising doctors and patients of the risk.A recently completed study...
• Improving Control of the Extrusion Spheronization Process
  of moistening, thereby affecting the particle size and hardness of the pellets obtained17.Granulation LiquidThe most commonly used granulating liquid is water, although in some cases the use of alcohol or a water-alcohol mixture has also been reported18. The effect of the alcohol content in a water-alcohol...
• A Closer Look at Form-Fill-Seal Technology
  5) microbiological standards during operations. Finally, a well-designed system should achieve Class 100 (ISO 5) airborne particle levels. Limitations of FFS Volatility and viscosity are two limiting factors of FFS technology. If the solvent is volatile in nature (e.g., alcohol, if alcohol content...
• Drug Development Through the Looking Glass
  hydrogenation and enzymatic reactions employing hydroxy nitrile lyases, aldolases and reducing enzymes like alcohol dehydrogenase. Enzyme reactions, for molecules that are reasonably water-soluble, provide close to 100% chemical and enantiomeric yield. DSM maintains three manufacturing sites (Venlo...
• To Succeed in Outsourcing Drug Packaging, Communicate Specs and Expectations
  below). Laser printers are best for paper-based or colored surfaces.” Complicating the printer-substrate relationship are special applications or demands placed on the printed surface. For example, Ravetto notes that a drug manufacturer may require that the code be resistant to an alcohol rub...

Engineering Web Search: Alcohol Validation