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Antibiotic Alkylation

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Development of C-H Insertion on Sulfonyl Compounds
high stereoselectivity, observed in alkylation of the six-membered products also is observed in the alkylation of the five-membered cyclic products.
Hexamethylenetetramine - Wikipedia, the free encyclopedia
The molecule behaves like an amine base, undergoing protonation and N-alkylation.
Mitomycin - Wikipedia, the free encyclopedia
C, finds use as a chemotherapeutic agent by virtue of its antitumour antibiotic activity.
Graduate Studies in the Life Sciences
This antibiotic covalently modifies DNA by alkylation of N-3 of adenine in the minor groove.
Graduate Studies in the Life Sciences
Molecular basis for sequence-specific DNA alkylation by CC-1065.
CSIRO PUBLISHING - Australian Journal of Chemistry
Analogues of the antibiotic SF-2312 with a 3-substituted 1-hydroxypyrrolidine moiety have been prepared from 1-benzyloxy-3-bromopyrrolidin-2,5-dione
Organic Chemistry Faculty - Ohyun Kwon
Asymmetric Syntheses of MDR Antibiotic Guanacastepene A and the Combinatorial Synthesis of its Analogs
Shen-Publications-patent
3. Shen, B., Liu, W.; Christenson, S.D.; Standage, S. Gene Cluster for Production of the Enediyne Antitumor Antibiotic C-1027.
Shen publication-2009

MIT Chemistry: Catherine L. Drennan
Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis, J. Am.

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