Aseptic Syringe Filling Machine

Conduct Research

• Safety Guides New Syringe Designs
  speeds, providing economic return for the time-space utilization of the facility and equipment.From an operational perspective, there must be a way to introduce pre-sterilized devices into the filling machine without contamination, to achieve consistent container closure integrity, to perform a 100%...
• A Tough Order to Fill
  By Bill Swichtenberg, Senior Editor Also affecting filling is manufacturers growing preference for convenient, disposable filling systems, which eliminate the need for clean-in-place and aseptic assembly of equipment, as well as cleaning validation. Althea is using this technology and buying new...
• The Needle Gets Another Shot
  process,” Paproski claims. Sterility assurance The boom in filling technologies and capacity coincides with a tougher regulatory stance on aseptic processing, particularly from the EMEA. DSM spent three years and “a fair amount of money” to conform all of its small- and large-molecule suites to EMEA...
• Fill 'Em Up
  for development and clinical runs, if not for all their sterile filling needs.Sterile liquid fill comes in two flavors: aseptic and terminally sterilized, but complex drug structures and formulations are slowly killing terminal sterilization. "These days, fewer and fewer drugs, and no biotech products...
• The Needle Gets Another Shot
  plenty of capacity out there,” says Novak, but room for more CMOs to participate in the market. Ben Venue Labs (Bedford, Ohio), a division of Boehringer-Ingelheim, is also contemplating syringe filling. VP of operations Dave Henderson says he sees a definite shortage of contract syringe fill...
• Low-Energy Electrons Have Pharma Beaming
  the technology to create a small aseptic zone within an automated machine, says Icke,. Sterile transfer. This has been used most often to sterilize syringe tubs as they move into an isolator. The e-beam system eliminates the use of hydrogen-peroxide vapor and links directly to the isolator. This has...
• Baxter Tackles Insoluble Solutions
  The company is also freezing drugs in a ready-to-use presentation to handle aseptic filling of unstable compounds such as cephalosporins and pencillin. Drugs are frozen within within their final containers then thawed out in a simple device at room temperature in five minutes, Tune says. Baxter had...
• The Needle Gets Another Shot
  Matthias Poslovski, technical sales director for Inova and Kugler for the Optima Group Pharma. Disposable components, popular in upstream processing, have slowly migrated downstream to aid sterile manufacturing. Tubing, valves, containers, fill nozzles and filters for filling are all available...
• What to Expect at Interphex 2007
  , a manufacturer of pharmaceutical packaging machinery, will be showing the GKF1400L capsule filler with liquid fill module, the FSX2020 nested syringe filler, the KKE2500 checkweigher with tablet feeder, the KWE4000 small package checkweigher, and the new FLT tabletop vial-filling system. ( A division...
• Dust-tight Powder Conveying, with a Twist
  the blender into a discharge adaptor above a filling machine. The conveyor can also be rerouted and attached to a mixer for drugs being made into paste form. Courtesy of Flexicon.Dust control was paramount. The company’s antibiotics are typically comprised of seven or eight powdered ingredients...

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