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  • Assay of Pharmaceutical Products
    Assay of products such as pharmaceutical suspensions and tablet coatings is a critical part of the Quality Assurance process. In some cases every batch of each product has to be tested, requiring 100% repeatability of results. Preparation of samples may involve disintegration of solids
  • Medical Device Link .
    Laboratory tests for drug metabolism compete (Madison, WI) has introduced a pharmacogenetic assay that detects mutations on the 2D6 gene, and may be poised to compete for the same market segment as Roche�s (Basel, Switzerland) CYP450 Amplichip. Third Wave�s Invader CYP450 2D6 panel
  • Medical Device Link .
    milliliters to microliters (and in some cases, nanoliters), with some test platforms using saliva, sweat, or urine to detect levels of analyte as low as picogram quantities. Advances in sample handling have also been important to assay improve ment. Reference labs such as Laboratory Corporation
  • Medical Device Link .
    and labor requirements. While most of the semiautomated instruments have automated the amplification and detection steps of the assay, the sample-processing step has not been automated, and this is typically the most troublesome step. In addition, first-generation NAAT sample-processing procedures
  • Medical Device Link .
    in instrumentation and assay technology, as well as how current industry trends affect product discovery, development, and execution. He also talks about the advantages of developing immunoassays in-house, how simpler instrumentation can help laboratories meet customer expectations, and the role of molecular
  • Medical Device Link .
    the amplification and detection steps of the assay, the sample-processing step has not been automated, which is typically the most troublesome step. In addition, first-generation NAAT sample-processing procedures are labor intensive, often requiring centrifugation and numerous manual pipetting steps
  • Medical Device Link .
    Calibration of an immunochemical assay for a new biological marker While a sound calibration strategy may require considerable resources, this key investment helps ensure that assays deliver reliable measurements. New biological markers discovered in clinical research can aid in diagnosis
  • Medical Device Link .
    . This presents enormous challenges for IVD manufacturers, since sample throughput and assay sensitivity are the immediate casualties when testing platforms are scaled down in size. While the new technologies being developed to meet this challenge (e.g., microfluidic systems, electronic detection systems

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