Capsule Formulation

Conduct Research

• Succeeding with Encapsulation Scaleup
  blend. Granulations can be even more challenging to scale up than direct-blend capsule formulations. Not only must process parameters be optimized, but the composition of the formulation, including components such as binder solution, must also be defined. The most important properties to consider...
• Interphex 2006 Preview: The Best of the Phex
  will exhibit a Pharma feeder and a working K-Tron PCS vacuum receiver. The Planeta continuous-motion capsule filler has over-encapsulation capabilities and a modular design that allows for different dosing units to be fitted at the same time. It can fill powders (including low-dose applications), pellets (up...
• Succeeding with Encapsulation Scaleup
  capsule formulations. In such cases, the active ingredient accounts for most of the fill weight, so scaleup depends on the API’s physical properties such as particle size distribution and bulk density.Although its chemical composition may be unchanged, API produced during early development stages...
• Demystifying GMPs for Nutritional Supplements
  and is not represented for use as a conventional food or as the sole item of a meal or the diet. The definition describes the variety of forms -- capsule, powder, softgel, gelcap, tablet, liquid, or other form -- by which these products can be ingested. In addition to laying the foundation for a regulatory...
• MICRO:Top 30 (November/December 2001)
  Filtration Products. Camarillo, CA. A series of microfilters is suitable for the filtration of etch baths, acids, bases, solvents, and metal and oxide CMP slurries. Available configurations include minicartridges for low-flow applications; capsule filters; 10-, 20-, 30-, and 40-in. cartridges; and 10...
• Preventing Development Bottlenecks---It's All In The Timing
  that," Ryan says. "They can't believe their product won't fit on our capsule filler. If we'd known of the problem earlier we could have told the customer about the delay, or tweaked the formulation to avoid the cost of new parts and time lost." It's also critical to inform any contract manufacturer...
• Demystifying GMPs for Nutritional Supplements
  as a conventional food or as the sole item of a meal or the diet. The definition describes the variety of forms -- capsule, powder, softgel, gelcap, tablet, liquid, or other form -- by which these products can be ingested. In addition to laying the foundation for a regulatory framework for dietary...
• Containment Technologies Group
  materials are not used in the formulation. Semi-solid spills and leaks also should be cleaned promptly. Capsules: Hard gelatin capsules, particularly banded capsules, present low potential for airborne micro-particle emissions unless the capsules break or unless process upsets in capsule filling deposit...
• MICRO: Product Technology News (April 2001)
  DI section features a high-purity total organic carbon reduction and DI polishing module, continuous recirculation, a digital resistivity monitor, a remote dispenser, and a 0.1-um final filter capsule. An optional built-in UV sterilizer is available for analytical-grade systems. Differential...
• Weighing and Dispensing: Do it Right
  volume scales are less accurate than their smaller siblings.Solid dosage and large-volume parenterals (LVP) are typical of operations that require handling large amounts of ingredients. In the case of a solid-dosage tablet compression or capsule-filling operation, the largest portion...

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