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...of the three hydrogen bonds in a Watson-Crick base pair, other guanine derivatives such as 7-deazaguanine may also be viable and attractive alternatives.9. Electrochemical Interrogation. For development purposes, cyclic voltammetry is the electrochemical method of choice for the nucleic acid...

...viable cell membranes. For example, it has recently been reported that using high-sweep-rate cyclic voltammetry to monitor species such as epinephrine or other biological species released from cells in culture can be performed with the microelectodes used in SECM.10 With the scanning capabilities...

...hybridization. This process brings the 5'-end of the signal probe containing electrochemically active ferrocene labels into close proximity to the electrode surface. The ferrous ion in each ferrocene group undergoes cyclic oxidation and reduction, leading to loss or gain of an electron, which...

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