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Active Hair-Bundle Motility by the Vertebrate Hair Cell
The hair bundle is both a mechano-sensory antenna and a force generator that might help the. vertebrate hair cell from the inner ear to amplify its responsiveness to small stimuli. To study active. hair-bundle motility, we combined calcium iontophoresis with mechanical stimulation of single hair
HCN Channels Are Not Required for Mechanotransduction in Sensory Hair Cells of the Mouse Inner Ear
biophysical evidence revealed the existence of. protocadherin-15 and HCN1 would place the HCN1 subunit in. mechanosensitive ion channels in hair cells of the vertebrate inner. the correct location to mediate hair cell transduction. We also note. ear over 30 years ago , the molecular composition
Coupling a sensory hair-cell bundle to cyber clones enhances nonlinear amplification
The vertebrate ear benefits from nonlinear mechanical amplification to operate over a vast range of sound intensities. The amplificatory process is thought to emerge from active force production by sensory hair cells. The mechano-sensory hair bundle that protrudes from the apical surface of each
Stepwise Morphological and Functional Maturation of Mechanotransduction in Rat Outer Hair Cells
, endolymph, normal mechanical stimulation, or an intact organ of Corti. outer hair cells. mechanoelectrical transduction. auditory. adaptation. myosin Ic. myosin IIIa. stereocilium links. Previous SectionNext Section. Introduction. The auditory hair cell is a mechanoreceptor, converting deflection
Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing
Inner ear hair cells detect sound through deflection. of mechanosensory stereocilia. Each stereocilium. is supported by a paracrystalline array of parallel. actin filaments that are packed more densely. at the base, forming a rootlet extending into the. cell body. The function of rootlets
Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible
the supranuclear cytoplasm of the hair cell. Hair cells can therefore repair, and recover from, neomycin-induced surface damage. Hair cells lacking myosin VI, a minus-end directed actin-based motor implicated in endocytosis, can also recover from brief neomycin treatment. Internalized annexin V
Calcium imaging of inner ear hair cells within the cochlear epithelium of mice using two-photon microscopy
or basal regions. Within one hour. of animal sacrifice, we find that outer hair cells demonstrate increased. fluorescence compared with surrounding supporting cells. This methodology. is then used to visualize hair cell calcium changes during. mechanotransduction over a region of the epithelium
Molecular Characterization of the Ankle-Link Complex in Cochlear Hair Cells and Its Role in the Hair Bundle Functioning
of the hair bundle toward the tallest stereocilia (i.e., in the excitatory direction) were reduced in outer but not inner hair cells. In both cell types, stimulation of the hair bundle in the opposite direction paradoxically resulted in significant transduction currents. The absence of ankle-link
Engineering Web Search: Hair Cell Top
Hair cell - Wikipedia, the free encyclopedia
Hair cell From Wikipedia, the free encyclopedia
Cell cycle - Wikipedia, the free encyclopedia
The cell cycle, or cell-division cycle, is the series of events that take place in a cell leading to its division and duplication (replication). The
n E w S A n d v i E w S Bad hair days for mouse PCP mutants...
and the local the sensory hair cells show a striking planar mal vasculogenesis and wound healing, and propagation of polarity from cell to cell.
These include the hair 35 6 to the view that three classes of signaling molecules govern and bristles that cover the body surface of the adult 36 7
LUTEar 2.0.9 Manual - Transduction Model ModulesIHC_Carney:...
Transduction Model ModulesIHC_Carney: Inner Hair Cell Synapse (1993) Example: Tests/Models/Transduction/Hair_Cell/PLockvsFreq.c
Endothelial Cells, Epithelial Cells, Smooth Muscle Cells,...
Media & Reagents Human Cell Media - Tissue Type Human Cell Media - Cell Type Human Cell Media - Alphabetical Human Cell Media - Media Compatibility
Center for Innovative Fuel Cell and Battery Technologies
Center for Innovative Fuel Cell and Battery Technologies
Science/AAAS | Science Signaling: Signal Transduction...
Database of Cell Signaling My Science Signaling N. R. Love et al., Nat. Cell Biol. 15, 222?228 (2013).