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  • Medical Device Link . Microspheres, part 2:
    ), buffer pH should be at, or slightly more basic than, IgG's isoelectric point (that is, pH 8), where the protein is in its most relaxed, compact form ( ). Gibbs and colleagues (Costar Corp., Kennebunkport, ME) say, "Binding is favored when pH is close, but not equal to, the pI [isoelectric point

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