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Baxter Tackles Insoluble Solutions
, typically uses cremofor (phytomenadione), a polyoxyethylated castor oil, as an excipient. The compound can cause severe swelling, so patients often require antihistamines when taking the drug. Then there is the matter of unstable materials. Proteins and peptides and even some mainstays
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Thermal Profiling Optimizes Printed Circuit Board Assembly
include different tolerated maximum temperatures, thermally sensitive components and different formulations of solder and flux. Lead-free assemblies compound the issues. Higher temperature requirements for lead-free reflow make it harder to avoid damage to sensitive components. To complicate matters
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Insulin: Beyond the Injection?
settling on just the right one, says Dr. Shingai Majuru, director of the company?s Pharmaceutics R&D. The company is now at the point of optimizing formulation, Majuru says, tweaking the compound so that it delivers the right amount of insulin and achieves desirable glucose levels. The critical question
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Getting Big Protection with Small Technologies
if they don t know what compounds you ve changed the molecular weight of, says Rittenburg. Knowing what we ve done to the compound allows us to get a very clean chromatogram that shows whether or not that material is present. Another person would never see it, because it s so far down in the noise
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Using RFID to Effectively Support the Pharmaceutical Supply Chain
data. Tags may be used not only to identify a product by type but by serial number as well, and thus support the tracking of individual consignments as they are passed to their ultimate destination. Furthermore, data specific to pharmaceutical shipments (such as compound name, formulation, quantity
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Drug Delivery: The "Great Equalizer"
safety, ease of administration, rapid absorption and onset of action, and, with the right compound, relatively low dose requirements. The intranasal delivery route has a lot going for it, but devices for delivering drugs into the nose are notoriously inaccurate. As recently as 1998, the most accurate
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Using Raman to Track API and Solid Dosage Forms During Drug Development
This quick, one-time registration gives you access to members-only site benefits. Many pharmaceutical quality programs fail to account for the fact that API forms can change during drug development. They may be the same compound, chemically, but have different particle sizes or morphologies
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Advances in Structural Acrylic Adhesives (.pdf)
referred to as the adhesive. component, and the benzoyl peroxide was supplied as an activator or accelerator. The benzoyl. peroxide was typically supplied as a paste in a plasticizer to facilitate mixing with the adhesive. 3. 299-51538. Typical commercial formulations provide a working time of a few