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Pharmaceutical Purification

 

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Biotechnology and pharmaceutical manufacturing services active pharmaceutical ingredients, sterilize biomedical components or materials, validate processes or packaging, and formulate drug or medicinal preparations on a contract basis.
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  • Pharmaceutical: Importance of TOC Measurements for Pharmaceutical Water Systems
    . The water treatment industry continues to develop and improve purification technologies and. while the systems can consistently produce Purified Water, Highly Purified Water and WFI, the. testing and documentation requirements have become more stringent. Pharmaceutical-grade. water systems must meet
  • Pharmaceutical: Updating International Standards For Pharmaceutical Waters
    back as 1989, the United States Pharmacopoeia (USP) and the Pharmaceutical Research and Manufacturers of America (PhRMA) began investigating alternatives to the wet chemistry tests. At that time, the principal focus was not on the water, but on the reliability of the water testing. Updating
  • Achieving Clean Pharmaceutical Water
    in pharmaceutical water systems. Depth- and membrane-type filters are often used. Final filtration as the sole treatment for water purification generally is not acceptable. If filters were used as the only barrier and a failure occurred, the water would be recontaminated with the entire volume
  • SMB Takes On Paclitaxel Purification
    in challenging purifications to remove impurities that are structurally similar to target compounds. Bioxel Pharma, Inc. has developed and implemented a fully automated, high throughput SMB process to remove cephalomannine from paclitaxel, an active pharmaceutical ingredient used in cancer drugs
  • Getting the Most from Coriolis Flowmeters in Pharmaceutical Processes
    flows than the larger alternative. The larger sensor will reduce the drain time for the piping system. Following are some guidelines for selecting (or not selecting) a straight-tube or bent-tube Coriolis flowmeter for the various phases of pharmaceutical manufacturing processes: General Flow
  • Improving Energy Efficiency in Pharmaceutical Manufacturing Operations Part II: HVAC, Boilers and Cogeneration
    Operational Excellence & Lean Six Sigma Cole, G.C. Pharmaceutical Production Facilities: Design and Application, 2nd Ed. Taylor & Francis, 1998. Novartis AG. Target and Results: Energy and Water Consumption, Novartis Health Safety and Environmental Group, 2004. Merck & Co., Inc. Personal
  • Application Notes: Minncare(R) Cold Sterilant - Sporicide Concentrate For Surface Disinfection in Pharmaceutical Cleanroom Environments (.pdf)
    Minncare Cold Sterilant is an effective disinfectant and sterilant for hard surfaces commonly found in pharmaceutical cleanrooms. Surfaces made from non-porous materials such as plastics, stainless steel or glass can be disinfected using Minncare Cold Sterilant solutions. Examples include counter
  • SMB Takes On Paclitaxel Purification
    is injected onto a ring of chromatographic columns at rotating points between the columns. At the same time, streams are withdrawn from the ring at rotating points, simulating the movement of the stationary bed. SMB has been applied to pharmaceutical separations [9-10] and is now in commercial use in FDA

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