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  • Think Small
    This conversion--from batch processes to continuous processes--would allow the use of smaller equipment with inherent lower capital costs. Continuous equipment also could be designed to be enclosed and cleaned easily, allowing the use of less costly production space because less of the environment
  • Graceful Scale Up of Mixing Systems
    When acquiring a process that involves one or several mixing steps, foresight for scale-up or expansion remains to be a subtle but important factor for long-term success. As production requirements grow, your ability to shift gears smoothly, quickly and efficiently is critical because it can spell
  • Going Small, Thinking Big
    the charge in modular systems. Drug firms are also experimenting with running many such reactor systems in concert for ever-increasing throughput ? often called numbering up rather than scaling up. The ability to number up also means that the transition from R &D to more large-scale production
  • Flow Stabilisation in Simulated Moving Bed Chromatography Using Flow Meters and Feedback Control
    Lab scale SMB systems are widely used for method development as well as for small scale production. Most of these systems are not equipped with detectors and controllers for maintaining desired product quality. Due to this fact, pumps with high accuracy and precision are required. Additionally
  • Medical Device Link . How to Handle Increased Production Volumes
    Medical Device & Diagnostic Industry , senior consultant of Excel Partnership, Inc. (Sandy Hook, CT), discusses some of the considerations for a small manufacturer ramping up for increased production. What are the most common problems that come up unexpectedly with start-up companies
  • Medical Device Link . Increasing antibody production with hollow-fiber bioreactors
    in an inoculated bioreactor, showing growth of monoclonal antibodies in the extracapillary space. PHOTO COURTESY UNISYN Antibody production using research-scale hollow-fiber bioreactors is generally not as efficient as using mice; quantities of antibody from a few to 100 milligrams are more often produced
  • Case History: Jackdaw Polymers Chooses the GP403-101 for New Technical Center
    on a system that replicates the production environment. The Acrison equipment consists of a main polymer feeder (GP 403-101), and two additive feeders (406 BDF 00; 405 BDF 11), all metering product into a small scale production twin screw extruder. The polymer feeder used in the centre at Jackdaw
  • Rheology Benefits for Blending and Extrusion
    and compounds. The C.W. Brabender Instruments, Inc. laboratory extruder systems cover the complete range of processing conditions for quality control, product development, research applications, pilot plant and small scale production. The extruders provide close test reproducibility acting as measuring

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