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...an injunction was issued prohibiting Bio-Rad from making, selling, or repairing MJ thermal cyclers in the United States. Under the terms of the current agreement, Bio-Rad 's thermal cycler supplier license has been amended to include the MJ Research products under dispute. Bio-Rad will receive permission...

...already validated PCR for specific clinical diagnostic applications. PCR was first performed in multiple water baths and then in programmable heat blocks or thermal cyclers. It offered the increased performance that clinical laboratories desired. Through in vitro amplification of specific target...

...and the working time or shelf life of a biological sample or laboratory reagent can be increased by keeping the substance at an optimal temperature. Instruments such as DNA cyclers, tunable laser diodes, and thermal-stress analyzers all require a capacity for cycling an object or sample through a range...

...preparation required before an amplified sample can be analyzed. Roche’s Cobas Amplicor analyzer was the first benchtop system to fully automate the amplification and detection steps of the PCR testing process on a single instrument (see Figure 1). It combines a thermal cycler, automatic pipettor...

...circuitry and thick-film technology have provided advances in this area in recent years --advances that address both price points and the design of the heaters, coolers, and temperature-monitoring technology employed in applications like thermal cyclers for DNA and RNA. The Quadrus Mini imager (left...

...that address both price points and the design of the heaters, coolers, and temperature-monitoring technology employed in applications like thermal cyclers for DNA/RNA. Industry miniaturization efforts have been accompanied by a need for greater motion-control precision in applications like...

...coolers, and temperature-monitoring technology employed in applications like thermal cyclers for DNA/RNA. Industry miniaturization efforts have been accompanied by a need for greater motion control precision in applications like microarrays and FISH. Thus, encoders with nanometer resolution are now...

...that address both price points and the design of the heaters, coolers, and temperature monitoring technology employed in applications like thermal cyclers for DNA/RNA. Industry miniaturization efforts have been accompanied by a need for greater motion control precision in applications like microarrays...

...had to be used with each cycle to perform the reaction. The second critical step was the development of thermal-stable polymerase and the automated Peltier-based thermal cycler. This development made PCR significantly easier to perform, and at this stage PCR started to find some limited clinical...

Technology October 2002. Tools for molecular diagnostics. The I-Core module by Cepheid (Sunnyvale, CA) is a complete, integrated thermal cycler and optical-detection device capable of performing and continuously monitoring the PCR reaction for amplifying DNA to detectable levels. Molecular diagnostics...

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