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  • Medical Device Link .
    of microspheres in a 1536-well microplate format, the partners envision a plate that could perform 1.5 billion assays simultaneously.Caliper Technologies Corp. (Palo Alto, CA) is working to integrate DNA separation, purification, and analysis onto a single microfluidic chip, and hopes to reduce assay
  • Medical Device Link .
    combination of fluorescent dyes. Planning to manufacture up to a million different types of microspheres in a 1536-well microplate format, the partners envision a plate that could perform 1.5 billion assays simultaneously. Caliper Technologies Corp. (Palo Alto, CA) is working to integrate DNA separation
  • Medical Device Link .
    assays (ELISAs) using prion protein�specific antibodies and peroxidase labels in the microplate format, as well as reagents for a Western blot analysis that is often employed as a confirmatory test. Following a brief review of the TSE problem for animal and human populations, this article
  • Medical Device Link . Commercialization of a chemiluminescence-based analyzer
    reactions have well below 15% quantum efficiency. The percentage of chemical reaction energy that is not dissipated by light emission is dissipated as heat or as kinetic collisional energy with other molecules in solution. The impact of luminescence quantum efficiency on the sensitivity
  • Medical Device Link .
    as many as eight wells from 96- or 384-well microplates in a process known as confluent sample analysis (CSA). In CSA, each sample, or well, is effectively labeled by the fluorescent signatures of the microsphere sets used for the bioassays. By sampling up to eight wells at a time, system users can
  • Medical Device Link .
    instruments that restrict sample throughput. In a typical PCR-lab arrangement using 96-well microplates, more than 10 thermocyclers can be coupled with a single fluorescence plate reader, making it possible to perform endpoint analysis of much greater numbers of samples. However, researchers attempting
  • Medical Device Link . DNA-chip technologies
    the accurate measurement, dispensing, and mixing of liquid volumes as small as 10 10 L (one millionth the volume of a well in a standard 96-well microplate) within interconnected microcapillaries on its single-use, plastic microchips. The company's microchips are trademarked under the Labcard name. Device
  • Medical Device Link .
    base. The procedure begins with converting a polymerase chain reaction product into a single-stranded DNA template and annealing a sequencing primer. Samples are held in a standard 96- or 384-well microplate. In one process, one or more samples can be analyzed for several different SNPs
  • Medical Device Link .
    a successful product launch and a marketing debacle. User-Driven Engineering One recent project, says Anderson, is illustrative of how well-defined market research can benefit a company. "The product in question was developed by a technology-driven company, and the engineers who had worked
  • Medical Device Link .
    each sample from a 96-well microplate to a designated microarray site; some 53 hours would be required to load 100 samples onto eight NanoChip cartridges. This loading time could be reduced by addressing amplicons from a 384-well plate onto four cartridges in the loader. In an effort to decrease