Sites:
Home > Technical Library > Manufacturing and Process Equipment > Materials Processing Equipment > Advances in Powder Micronization Technology for the Pharmaceutical Industry

Advances in Powder Micronization Technology for the Pharmaceutical Industry

From Hosokawa Micron Powder Systems

The demand for pharmaceutical materials including finely ground active substances and excipients is growing. Injectable drugs and dry powder inhalants require particle-size distributions in the range of D97 of 2-20 microns, with a steep distribution curve and a minimum of fine and oversized particles. This can be accomplished by either wet or dry processes.

Conventional dry size reduction of pharmaceutical powders is accomplished by impact size reduction. Equipment commonly used falls into the category of either mechanical impact mills or fluid-energy impact mills. Examples of mechanical impact mills are hammer and screen mills, pin mills, and air-classifying mills. Spiral jet mills and fluidized-bed jet mills are examples of fluid-energy impact mills.

Read the Whole Article
Products & Services
Crushers
Industrial Crushers reduce large rocks into smaller rocks, gravel, or rock dust. Crushers may be used to reduce the size, or change the form, of waste materials so they can be more easily disposed of or recycled, or to reduce the size of a solid mix of ra
Grinding Mills and Pulverizers
Grinding Mills and Pulverizers are machines that grind materials into fine powders, tiny shards, shapes, or granules on a continuous basis. Often, they are used to process items that are 2 inches (5 cm) in size
Powder Compacting Equipment
Powder compacting equipment is used to shape powders as part of a forming process and to compress a wide range of materials into compact shapes for ease of transportation and handling.
Powder and Solids Blenders
Powder and solids blenders produce a uniform mixture of dry or powdery materials. They are designed for industrial and laboratory environments, and provide either batch or continuous blending.
Conical Screw Mixers
Conical screw mixers use a rotating screw that progresses around the periphery of a conical hopper. The screw lifts solids from the bottom of the hopper to the top, where the mixture flows by gravity back into the screw.
Product Announcements
Pallmann Industries - Size Reduction Machines For The Wood Industry
PALLMANN has been manufacturing size reduction machines and complete preparation systems for the panelboard- and the wood processing industry for decades. (read more)
Custom Processing Services - Micronizing Mill Services...by Custom Processing
CPS offers micronizing to ultra-fine particle-sizes of both technical and cGMP grade materials. A variety of air-jet mills utilizing innovative technology from world-renown mill manufacturer NETZSCH... (read more)
Pallmann Industries - Economic debarking of logs
Economical debarking at high capacity Reliably operation and bark removal Modular design and simple maintenance... (read more)
Pallmann Industries - Preparation of cellulose and cellulose ether
Cellulose powders ground with Precision Knife Mills have a large surface area and improve the reactiontime and the fill weight in the reactor. For each grinding step PALLMANN has the most suitable... (read more)
Munson Machinery Company, Inc. - Vee-Cone Blender Discharges Fully, Sanitizes Fast
A new Model VB-10-316S Sanitary Vee-Cone Blender with 10 cu ft (283 liter) capacity has been introduced by Munson Machinery. The smooth internal surfaces are free of baffles, shafts and bearings,... (read more)
Munson Machinery Company, Inc. - Sanitary Rotary Lump Breaker
A Sanitary Lump Breaker from Munson Machinery features side removal bed screens for rapid, thorough wash down. The all-stainless, low profile unit, Model RDC1515-SS, reduces agglomerates and friable... (read more)
Munson Machinery Company, Inc. - Attrition Mill Reduces Particles
A new Model SK-24-MS Attrition Mill from Munson Machinery reduces friable chemicals and minerals, as well as metal powders, wood flour, fertilizers, insecticides and fibers, producing particles within... (read more)
Sturtevant Inc. - Food Grade Mills by Sturtevant
Sturtevant's Simpactor® Pin Mill is the perfect solution for milling dry powder food ingredients such as MSG, Whey and Amino Acids to precise fine particle sizes of 50-200 mesh. This unit can be... (read more)
Sturtevant Inc. - Fine Milling of Nutraceutical Powders
Sturtevant’s Simpactor® Pin Mill is the perfect solution for milling nutraceuticals to precise fine particle sizes of 50-200 mesh. This unit can be designed to USDA Standards. (read more)
 
Topics of Interest

Introduction Grinding is the last stage in the process of comminution; in this stage the particles are reduced in size by a combination of impact and abrasion, either dry or in suspension in water.

Operational Excellence & Lean Six Sigma Basic types of media mills Dry media mills for finest powders Wet media mills for slurries Powder Blending From Art to Science Digital Insights: At Last:...

Size reduction mills are used widely throughout the pharmaceutical industry for the reduction of active ingredients (API's), as well as bulk pharmaceuticals (BPI's) and excipients such as lactose,...

Dispersion, colloid and roller mills are used to reduce solid products to a desired particle or aggregate size in dry or slurry forms. Colloid mills use discs or rotors that spin at very high speeds...

Conical Screen Mills (also referred to as Cone Mills) are gentle size reduction mills which are often used to precondition the material prior to its entry into a process, either by delumping or coarse...