From Cambridge Polymer Group, Inc.
Benzoyl peroxide (BPO) is added to bone cement as a radical initiator for the methyl methacrylate
monomer. BPO is highly reactive and degrades readily, with a temperature dependent half-life of one
hour at 92 °C and one minute at 131 °C. The degradation products, benzoic acid and oxygen, are not
significantly toxic, but the BPO remaining to initiate the polymerization is decreased, leaving unreacted
monomer in the cement, and the potential for incomplete cure.
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