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Atomic Force Microscopy of Microbial Cells (AN50)

From Veeco Instruments
 

 

Microbial cells (bacteria, yeasts and fungal spores) are surrounded by fairly rigid cell walls which play several vital functions: protecting the cytoplasm from the outer environment, providing the cell with a rigid structure, determining the cell shape and controlling cell adhesion phenomena. Microbial adhesion processes have major consequences in natural environments (symbiotic interactions, biofouling), medicine (infections), and biotechnology (bioremediation, immobilized cells in bioreactors). Therefore, understanding the structure, properties and functions of microbial cell surfaces is of great significance for both fundamental and applied research.

Light and electron microscopies have long been recognized as the key techniques to look at microbial cells. Light microscopy is useful for counting and identifying the cells as well as for determining their general morphological details; but because the resolution is limited to the wavelength of the light source, information at the nanometer level is not accessible.

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