By Nick Phillips, CH2M Hill Lockwood Greene Every pharmaceutical manufacturing plant features an area in which raw materials are weighed and transferred to clean containers. This area goes by various names, including Weighing, Weighroom, Central Weigh, Pharmacy, Dispensary, Dispensing, Fractionation and Subdivision. No matter what it’s called, its design is essential. This article outlines some best practices for design, layout and operation of these areas. Three basic principles should drive the design of any pharmaceutical weighroom: In the past, convenience dictated the placement of weighrooms, traditionally located right near warehouses where materials were stored. Today, the weighroom is viewed as the entry point to manufacturing and the transition point for materials coming from the warehouse and entering process areas, so specific criteria will determine the best location. The typical weighroom is made up of three sections: raw material
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