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From Fluid Handling

When it comes to pumping high-purity fluids, not any pump will do. Processors of pharmaceuticals, foods and beverages and biological compounds must consider pumps in ways that may not be particularly relevant to processors in other sectors of the chemical process industries (CPI). For instance, considerations such as cleanability, pump style, materials of construction, process connections and other areas where contamination can be tightly controlled are essential to ensuring acceptable operation.

Many regulatory agencies and industry associations have some input in specifying and setting standards for high-purity equipment. Among them, the International Organization for Standardization (ISO; Geneva; iso.org) publishes global standards for manufacturing pharmaceuticals and other products that must meet strict standards of cleanliness. The 3A sanitary standards, administered by the International Assn. of Food Industry Suppliers (IAFIS; McLean, Va.; iafis.org), provide guidelines for the application and manufacture of cleanable equipment. These standards, originally developed by the dairy industry, are now widely cited when designing sanitary systems.

Pharmaceutical manufacturers in the U.S. must also conform to current Good Manufacturing Practices (cGMP), as mandated by the U.S. Food and Drug Administration (FDA; Washington, D.C.; fda.gov). Bioprocessing guidelines, ASME-BPE-97, published by the American Soc. of Mechanical Engineers (ASME; New York; asme.org) are...


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© 2014 Chemical Engineering

Products & Services
Double Diaphragm Pumps
Double diaphragm pumps are positive displacement pumps that compress fluid by decreasing the volume of a chamber containing the fluid.
Hand Pumps and Foot Pumps
Hand pumps and foot pumps are manually operated pumps that can driven by hand or foot via a handle or lever. 
Mechanical Vacuum Pumps and Systems
Mechanical vacuum pumps and systems contain devices such as pistons, claws, scrolling spirals, and diaphragms to isolate and compress air.
Condensate Pumps
Condensate pumps are used to collect and transport condensate back into a steam system for reheating and reuse, or to remove unwanted condensate from an HVAC or appliance collection pan.

Topics of Interest

Pumping fluids containing microorganisms - especially in the areas of pharmaceuticals, foods and beverages, and waste water purification - has always been a problem in the chemical process industries.

While not as common as centrifugal pumps in the CPI, gear pumps play important roles in handling many of today’s more difficult-to-pump fluids. Because they operate at lower speeds —...

Medical Device & Diagnostic Industry The positive displacement metering pump is generally the first choice for providing precise and repeatable flow in many medical device fluid-dispensing...

Today, two main types of pump dominate the scene in the chemical process industries: positivedisplacement pumps and impeller pumps. For pumping applications that involve highly volatile fluids, the...

When it comes to measuring high-purity fluids, not all flowmeters are created equal. In addition to the accuracy, repeatability and reliable operation that is required of any flowmeter, the device...

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