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An Evaluation of Four Commercial HPLC Chiral Detectors
(Chromatography)
From this Article:
With increasing frequency, new drug candidates being introduced into pharmaceutical drug pipelines are chiral. Often only one enantiomer exhibits the desired biological activity and the other...
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Analysis of Automotive Fluids Using FTIR
(Lab Equipment and Scientific Instruments)
From this Article:
The liquid sample is one of the most common types of samples submitted for analysis and comprises a vast array of pure compounds and solutions. As an example, several liquids are used in an automobile...
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Analysis of Automotive Polymers Using FTIR
(Lab Equipment and Scientific Instruments)
From this Article:
There are several criteria that are important to the professional chemist and the laboratory professional. These include sample preparation, reproducibility, high sensitivity, and versatility....
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Applications for the IMV-4000 Multi-Channel Infrared Microscope
(Lab and Test Equipment)
From this Article:
Over the last two decades, IR microscopy has been widely utilized to identify increasingly smaller samples. Incorporation of a linear array detector and rapid scanning in a FT-IR microscope permits...
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Automated Sun Protection Factor (SPF) Analysis of Sunscreen Using UV-Vis
(Lab Equipment and Scientific Instruments)
From this Article:
The increasing awareness of the risks of skin cancer with sun exposure requires that sunscreen products be appropriately tested and labeled. The numerous possible sunscreen formulations demands that a...
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Carbon Nanotube Analysis by Raman Spectroscopy
(Lab Equipment and Scientific Instruments)
From this Article:
Carbon nanotubes are fullerene-type structures which consist of graphene cylinders closed at either end. A nanotube can be thought of as a hexagonal network of carbon atoms that has been rolled up to...
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CD Detection of Myoglobin Structure During an Automated pH Titration
(Lab Equipment and Scientific Instruments)
From this Article:
A protein can be thought of as a hetero-polymer, often hundreds of units long, composed of twenty different amino acids. The sequence of amino acids dictates the well-defined native 3-D structure,...
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Circular Dichroism Spectrometry for the Analysis of Amphetamines
(Lab Equipment and Scientific Instruments)
From this Article:
Amphetamines are synthetic drugs that stimulate the central nervous system. They are structurally similar to ephedrine, a natural stimulant found in plants and to the hormone adrenaline. They are...
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Detection of Amino Acids Using HPLC with CD Detection
(Chromatography)
From this Article:
A tetrahedral carbon atom with 4 distinct constituents is said to be chiral. Chirality describes the ability of a molecule to rotate the plane of polarized light either to the right (dextrorotatory)...
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Detection of Chiral Compounds Using HPLC with CD Detection
(Chromatography)
From this Article:
Chiral detectors provide valuable information since they only respond to optically active compounds. This allows the researcher to differentiate enantiomers. A sensitivity comparison between the two...
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Detection of Chiral Drugs Using HPLC with CD Detection
(Chromatography)
From this Article:
Many molecules made up of the same number and type of atoms come in two forms commonly referred to as left-handed and right-handed isomers. This is not just some interesting quirk of nature:...
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Detection of Nitroarenes in Diesel Exhaust Using HPLC with UV and Fluorescence Detection
(Chromatography)
From this Article:
A family of polyaromatic hydrocarbons (PAHs) known as nitroarenes are present in automobile exhaust. These species are known to be highly mutagenic and carcinogenic. Thus, it is very important to...
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Dispersive Raman for the Identification of Contaminant Particles in Ink Jet Cartridges
(Lab Equipment and Scientific Instruments)
From this Article:
Statistics have long supported the dominance of inkjet printing. From sales of $500 million in the early 90's to a record-breaking $14 billion in inkjet cartridge sales projected in 2001. Today, 7 out...
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Fluorescence Detection of Counterfeit US Currency
(Lab Equipment and Scientific Instruments)
From this Article:
United States currency is the most counterfeited currency in the world with Canadian money a close second, these currencies popular due to their status as a 'hard' currency, similar to gold. Large...
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Gemstone Identification Using Raman Spectroscopy
(Lab Equipment and Scientific Instruments)
From this Article:
Gemstones and semi-precious stones have been modified for centuries to make them more colorful, more eye-catching, and easier to work with. One such technique is heat treating (the most common) to...
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Infrared Microscopy for the Analysis of Polymer Laminates in a Juice Bottle
(Lab and Test Equipment)
From this Article:
Modern polymers are seldom used as pure materials, more often mixtures of different polymers are combined to give the desired physical characteristics. For example, the rigidity of polystyrene is...
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Nanospectroscopy Using a Near-Field Scanning Microspectrometer
(Lab Equipment and Scientific Instruments)
From this Article:
Recent years have seen explosive growth in the use of organic materials, composites, or organics bound to an inorganic substrate, to solve engineering problems that traditionally were approached only...
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Pharmaceutical Tablet Characterization by NIR Imaging
(Lab Equipment and Scientific Instruments)
From this Article:
The use of near-infrared (NIR) spectroscopy in the pharmaceutical industry has grown rapidly in the past decade. The IMV-4000 Infrared Multichannel Viewer integrated with a NIR capable FT/IR-4000 or...
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Quantitative Analysis of Powdered Solids with FTIR-ATR
(Lab Equipment and Scientific Instruments)
From this Article:
Infrared quantitative analysis is an everyday requirement for the analytical laboratory. While liquid solutions are a common sample, mixtures of powdered components also exist and it is often...
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Rapid Peptide Separation by Supercritical Fluid Chromatography (.pdf)
(Separations)
From this Article:
Interest in supercritical fluid chromatography (SFC) applications is growing due to its ability to reduce analysis times, organic solvent consumption and waste production. SFC is well established for...
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Secondary Structure Analysis (SSE) Software for Infrared Interpretation and Modeling of Proteins
(Lab Equipment and Scientific Instruments)
From this Article:
As the last strands of the human genome project unravel, the focus now turns to proteomics. There are several instrumental methods to analyze protein chemistry and there is particular interest in the...
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Secondary Structure Analysis of Proteins Using IR Imaging
(Lab Equipment and Scientific Instruments)
From this Article:
The IMV-4000 enables infrared imaging by a figure of two or more faster than using a conventional single element detector. A technique that quickly analyzes the results is also desirable. JASCO has...
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Thermal Denaturation of Hen-Egg Lysozyme with Concurrent CD and Fluorescence Detection
(Lab Equipment and Scientific Instruments)
From this Article:
Studies on the mechanisms of protein folding are currently focusing on the role of partially folded states. A number of biologically and functionally important proteins have marginal stability in...
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