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  • IR for the Masses
    Operational Excellence & Lean Six Sigma an improved Universal Attenuated Total Reflectance (UATR) accessory, designed to help simplify measurement of solid samples and to minimize variations in measurements, between different users and different samples; a new fiber optic NIR probe with a user
  • Ultrasonics Beats Optical Methods for Measuring Some Critical Attributes
    are available for different types of the analysis: standard sample cells of 1ml in capacity, flow-through cells that allow the carrying out of the analysis in-flow, cells with automatic sampling, cells with small volume capacities (as low as 0.03ml) and cells that allow semi-solid samples
  • Rapid Microbiological Methods for a New Generation
    By Michael J. Miller, Ph.D., Senior Research Fellow, Eli Lilly and Co. One of the greatest contributions to the field of microbiology came from the kitchen. In the 1880s, scientist Walter Hesse was searching for a solid medium that could be used to cultivate bacteria. The material had to be stable
  • ICH Guidances (Already) Show Their Age
    date back well over a decade and pre-dated the QbD concept. This series will examine the various ICH guidelines and discuss their applicability to PAT/QbD as written. The first to be examined is the ICH Guidance for the analysis (for release) of solid dosage forms: Guidance ICH Q2 (R1) [formerly
  • Powder Blending From Art to Science
    This quick, one-time registration gives you access to members-only site benefits. Spectral Dimensions has previously used the technique to analyze finished products in much the same way. NIR Chemical Imaging can rapidly determine the distribution of the constituents of a solid dosage form
  • Combining Size and Shape Analysis
    characterize. the particles and eliminate sizing errors resulting from poor sample dispersion and the presence of. agglomerates and contaminants. Particles in bulk solid materials come in a. huge variety of shapes, such as spherical,. cubic, pyramidal, and elongated. Several. ways of characterizing
  • An Introduction To The Physical Characterization of Materials by Mercury (.pdf)
    intruded into the sample as a function of applied pressure) is indicative of various characteristics of the pore space and is used to reveal a variety ofphysical properties of the solid material itself. The information that follows falls into three main categories: I) instrument theory and its

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