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Technical Articles

CNI Laser(Changchun New Industries Optoelectronics Co., Ltd.) has published these technical articles:

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A covert print-and-read system is demonstrated based on NIR-to-NIR upconversion luminescence. Inks activated with Yb3+/Tm3+ doped ß-NaYF4 upconversion nanoparticles were used to print covert...
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A novel total internal reflection fluorescence (TIRF) spectrometric technique using a dual optical fiber sample cell was developed. A conventional silica optical fiber was used for exciting...
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Photochromic LC-polymer composites containing azobenzene chromophores with thermally stableZ-isomers. Confocal laser method for quantitative evaluation of critical optical properties of toric...
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The design and manufacture of intraocular lenses (IOLs) depend upon the identification and quantitative preclinical evaluation of key optical properties and environmental parameters. The confocal...
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Fluorescent proteins photoswitchable with noncytotoxic light irradiation and spectrally distinct from multiple available photoconvertible green-to-red probes are in high demand. We have developed a...
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High-sensitivity detection of trace amounts of c-erbB-2 oncogene was reported to be equal to or surpass the ability of CA 15-3 for early diagnosis and/or follow-up recurrent screening of breast...
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This study reports on an integrated microfluidic system capable of counting CD4+/CD8+ T lymphocytes from a whole blood sample, which may be further applied for the rapid screening of the human...
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The Gram-negative Aggregatibacter actinomycetemcomitans and Fusobacterium nucleatum are major causative agents of aggressive periodontal disease. Due to increase in the number of antibiotic-resistant...
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A combination of near-infrared (NIR) spectroscopy, Raman microscopy, and atomic force microscopy (AFM) was used to analyze the adsorption behavior of petroleum macromolecules (asphaltenes) on an iron...
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Assessment of molecular biomarkers expressed in cells and tissues can inform scientists and clinicians of physiological and disease processes. Optical techniques can quantitatively and noninvasively...
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Stimuli-responsive drug delivery systems were obtained by encapsulating near-infrared (NIR) sensitive hollow gold nanoshells (HGNs) together with the molecule to be released into biodegradable...
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Selective Plane Illumination Microscopy (SPIM) is an imaging technique particularly suited for long term in-vivo analysis of transparent specimens, able to visualize small organs or entire organisms,...
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Purpose: To present a proof-of-concept study on the development and implementation of an innovative confocal laser method platform for precise quantitative evaluation of critical optical properties...
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Complex motor behaviors are thought to be coordinated by networks of brain nuclei that may control different elementary motor programs. Transparent zebrafish larvae offer the opportunity to analyze...
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A depth resolved hyperspectral imaging spectrometer can provide depth resolved imaging both in the spatial and the spectral domain. Images acquired through a standard imaging Fourier transform...
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Neurons in different locations across the cortex are connected through polysynaptic networks involving both excitation and inhibition. To probe the functional effect of such networks, we used...
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Single particle tracking is a powerful tool to investigate the function of biological molecules by following their motion in space. However, the simultaneous tracking of two different species of...
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Neurological respiratory insufficiency strongly correlates with mortality among rodents infected with West Nile virus (WNV), which suggests that this is a primary mechanism of death in rodents and...
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Little is known about how neuron firing recorded in vivo retrogradely influences synaptic strength. We injected the firing of a rat hippocampal neurogliaform cell (NGFC), a widely expressed GABAergic...
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Genetically encoded photosensitizers are a promising optogenetic instrument for light-induced production of reactive oxygen species in desired locations within cells in vitro or whole body in vivo....
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Ischaemic stroke patients treated with Selective Serotonin Reuptake Inhibitors (SSRI) show improved motor, cognitive and executive functions, but the underlying mechanism(s) are incompletely...
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Recent evidence suggests the intriguing possibility that midbrain dopaminergic (DAergic) neurons may use fast glutamatergic transmission to communicate with their postsynaptic targets. Because of...
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Combining voltage and Ca2+ imaging allows the correlation of electrical and chemical activity at sub-cellular level. Here we describe a novel apparatus designed to obtain simultaneous voltage and Ca2+...
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Optimized conditions for measuring the multiple distances within a single molecule by switchable FRET increase the temporal resolution of the method by an order of magnitude. Furthermore, linked...
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We demonstrate an integrated micro-optofluidic platform for real-time, continuous detection and quantification of airborne microorganisms. Measurements of the fluorescence and light scattering from...
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Corticospinal pyramidal neurons mediate diverse aspects of motor behavior. We measured spike-related electrophysiological properties of identified corticospinal neurons in primary motor cortex slices...
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We have experimentally demonstrated that the emission of visible light from the polymer matrix doped with luminescent dye and gold nanoparticles (GNPs) can be enhanced with the use of surface plasmon...
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The current study presents a new miniature microfluidic flow cytometer integrated with several functional micro-devices capable of viral sample purification and detection by utilizing a magnetic...
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Targeted sequence enrichment enables better identification of genetic variation by providing increased sequencing coverage for genomic regions of interest. Here, we report the development of a new...
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We describe a setup including a microscope to study volumes of a few µm3 by static and dynamic light scattering (DLS) in a backscattering configuration. Light scattered by individual objects of...
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A microscope-based label-free microfluidic cytometer capable of acquiring two dimensional light scatter patterns from single cells, pattern analysis of which determines cellular information such as...
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Holography is divided into two processes which are recording and reproduction, the interference fringes is generated on the holographic plate through the superposition between the reference light and...
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The stumbling block of employing Raman imaging in nanoscience and nanotechnology is the diffraction-limited spatial resolution. Several approaches have been employed to improve the spatial resolution,...
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Zinc oxide is synthesised at low temperature (80°C) in nanosheet geometry using a substrate-free, single-step, wet-chemical method and is found to act as a blue-white fluorophore. Investigation by...
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We report an experimental study of the temporal and spatial dynamics of shock waves, cavitation bubbles, and sound waves generated in water during laser shock processing by single Nd:YAG laser pulses...
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The core subcompartment of the nucleus accumbens (NAcore) contributes significantly to behavioral responses following motivationally relevant stimuli, including drug-induced, stress-induced, and...
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Optogenetics is a booming multidisciplinary bioengineering technology. It has the characteristic of high spatial-temporal resolution and cell-type specific. It overcomes the disadvantages of...
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The locus coeruleus (LC) is the sole source of noradrenergic projections to the cortex and essential for attention-dependent cognitive processes. In this study we used unilateral optogenetic silencing...
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A specific memory is thought to be encoded by a sparse population of neurons. These neurons can be tagged during learning for subsequent identification3 and manipulation. Moreover, their ablation or...
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Novel types of photochromic liquid crystalline (LC) polymer-based composites containing chiral photochromic azobenzene moieties were elaborated. For this purpose, a new chiral azobenzene-containin g...
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Controlled activation or release of biomolecules is very crucial in various biological applications. Controlling the activity of biomolecules have been attempted by various means and controlling the...
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To investigate the interplay between microscopic dynamics and macroscopic rheology in soft matter, we couple a stress-controlled-rheometer equipped with a Couette cell to a light scattering setup in...
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We present a new design of an imaging cytometer for high content bioanalysis, which is equipped with a low-cost linear complementary metal oxide semiconductor (CMOS) imager (running at =40kHz). The...
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Sequential barcoded fluorescent in situ hybridization (seqFISH) allows large numbers of molecular species to be accurately detected in single cells, but multiplexing is limited by the density of...
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A synthetic method to prepare novel multifunctional core-shell-structured mesoporous silica nanoparticles for simultaneous magnetic resonance (MR) and fluorescence imaging, cell targeting and...
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We demonstrate vertical cross-sectional (XZ-plane) images of near-infrared (NIR) fluorescence with a handheld dual axes confocal endomicroscope that reveals specific binding of a Cy5.5-labeled peptide...
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Optical control of neuronal activity has a number of advantages over electrical methods and can be conveniently applied to intact individual neurons in vivo. In this study, we demonstrated an...
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OBJECTIVE: To investigate the influence of continuous near-infrared (CNI) laser to potassium ion channels on retinal ganglion cell (RGC). METHODS: Experiment study. Porcine RGC was cultured with...
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Digital holography is an emerging technology that can generate complex light patterns for controlling the excitability of neurons and neural circuits. The strengths of this technique include a high...
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A high throughput 3D image cytometer have been developed that improves imaging speed by an order of magnitude over current technologies. This imaging speed improvement was realized by combining...
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The strong phototoxicity of the red fluorescent protein KillerRed allows it to be considered as a potential genetically encoded photosensitizer for the photodynamic therapy (PDT) of cancer. The...
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Spirooxazine could be used as optical storage medium due to the excellent photochromic characteristic. In this paper, dynamics of holographic grating recording in spirooxazine-doped PMMA polymers was...
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We show a different approach to perform near-field Raman imaging with sub-diffraction limit spatial resolution. In this approach, a dielectric microsphere is trapped by the excitation laser through...
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Super-localization microscopy encompasses techniques that depend on the accurate localization of individual molecules from generally low-light images. The obtainable localization accuracies, however,...
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Optogenetics is a technical methodology that allows direct light-based manipulation of genetically specified cells. Optogenetic methods have provided novel insights into the role of defined neuronal...
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Localized subcellular changes in Ca2+ serve as important cellular signaling elements, regulating processes as diverse as neuronal excitability and gene expression. Studies of cellular Ca2+ signaling...
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A new fiber optic fluorescence spectroscopic method using a liquid core waveguide (LCW) as an excitation element has been developed for detecting a fluorescence compound absorbed on an optical fiber's...
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The molecular wire-appended naphthoquinone 1-[15-(3-methyl-1,4-naphthoquinone-2-yl)]pentadecyl disulfide [(NQ(CH2)15S)2] has been incorporated into the A1A and A1B sites of Photosystem I (PS I) in the...
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We combine super-resolution localization fluorescence microscopy with transmission electron microscopy of metal replicas to locate proteins on the landscape of the cellular plasma membrane at the...
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We present a novel approach which allows simultaneous measurement of the velocity field and the interface profile close to a composite liquid-gas and solid-gas interface. The proposed scheme is the...
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Onychomycosis, a fungal infection of the finger or toenails, is predominantly caused by Trichophyton rubrum. Treatment is difficult due to high recurrence rates and problems with treatment compliance....
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Materials that convert visible light into ultraviolet radiation have recently been studied for potential application to new catalytic and antimicrobial technologies. Conversion efficiencies of...
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As a sophomore at Juniata College, I was enrolled in an advanced course in microscopy where I took immediate liking to the subject. Although interested in the biological applications of the field, I...
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Fast and accurate pathogen detection in aquatic environments is challenging in many biomedical studies and microbial diagnostic applications. In this study, we developed a real-time, continuous, and...
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Fluorescence ghost imaging with pseudothermal light...
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We have mapped intracortical activity in vivo independent of sensory input using arbitrary point channelrhodopsin-2 (ChR2) stimulation and regional voltage sensitive dye imaging in B6.Cg-Tg...
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Nickel superoxide dismutase (NiSOD) is a recently discovered superoxide dismutase that utilizes the NiIII/NiII couple to facilitate the disproportionation of O2*- into H2O2 and O2. A key structural...
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The sculpting of membranes into highly curved vesicles is central to intracellular cargo trafficking, yet the mechanical activities of trafficking proteins remain poorly understood. Using an optical...
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We achieve active control of interfacial phenomena by optically trapping the interface using the gradient forces of a strongly focussed laser beam parallel to the interface. We illustrate our...
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We have synthesized a pH-dependent, NIR-sensitive, reduced graphene oxide (rGO) hybrid nano-composite via electrostatic interaction with indocyanine green (ICG) which is designed not only to destroy...
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A new optical-fluorescence microscopy technique, called HR-OPFOS, is discussed and situated among similar OPFOS-implementations. OPFOS stands for orthogonal-plane fluorescence optical sectioning and...