Hamilton Introduces the ALLDROP nanoDispenser
Featured Product from Hamilton Company

Hamilton, a global leader in precision engineering and laboratory automation, proudly announces the launch of the ALLDROP® nanoDispenser—a innovative solution that propels liquid handling technology into the nanoliter realm. This cutting-edge solution sets a new benchmark in precision, compliance, and efficiency in workflows across pharmaceutical, biotech, and diagnostic industries.
“The ALLDROP® nanoDispenser is a game-changer for industries that demand unparalleled precision and traceability in their workflows. with unmatched accuracy, real-time traceability, and seamless integration, we’re empowering scientists and manufacturers to break new ground in research and production,” said Thomas Clapes, Product Manager at Hamilton.
Breaking the barriers of traditional microliter systems, the ALLDROP® nanoDispenser is powered by the PIPEJET® technology, a non-contact piezo-actuated dispensing mechanism capable of delivering volumes as small as 20 nanoliters. With a coefficient of variation (CV) below 3%, it sets a new standard for precision in nano liquid handling, expanding the possibilities for groundbreaking scientific research and development.
Coupled with SMARTRESERVOIR® Technology, the system not only maintains stable pressure across diverse liquid types, but also streamlines liquid management with advanced automation. During setup, the system automatically primes the liquid line to the dispensing nozzle with minimal waste, ejecting only a few drops. This precision is made possible by software that actively monitors the liquid meniscus throughout the process, ensuring accuracy and efficiency while conserving valuable reagents.
The ALLDROP® integrates effortlessly into any automation platform. Amagnetic coupling system enabling rapid printhead changes revolutionizes maintenance, offering effortless cleaning, and streamlined reagent swaps—all designed to minimize downtime and maximize productivity. A compact Control Box simplifies printhead management and scheduling. Additionally, pre-assembled cables and intuitive software further enhance ease of use, allowing laboratories to transition seamlessly from setup to full productivity.
In today’s regularitory landscape demanding transparency and accountability, the ALLDROP® nanoDispenser establishes a new standard with real-time monitoring, 100% process checks, and rapid data logging. Fully aligned with ISO 23783 and GxP standards, the system automates processes that traditionally rely on labor-intensive manual adjustments and gravimetric checks, providing unmatched traceability and audit readiness
The inclusion of gRPC technology elevates the ALLDROP® by enabling seamless platform integration. Supporting multiple programming languages, gRPC ensures effortless setup, allowing the ALLDROP hardware to integrate directly into existing automation platforms with minimal effort.
"The ALLDROP® nanoDispenser isn’t just a step forward—it’s a leap into the future of liquid handling”. said Matt Hamilton, CEO of Hamilton. “This innovation provides laboratories and manufacturers with the precision and efficiency needed for ultra-low volumes, overcoming the common challenges that often plague breakthroughs.”
Hamilton’s ALLDROP® nanoDispenser underscores the company’s commitment to delivering transformative solutions that empower laboratories worldwide to achieve scientific breakthroughs while maintaining rigorous compliance and operational excellence.