Dissolved carbon dioxide (DCO?) is a critical process parameter (CPP) in biopharma production processes according to PAT guidelines. By influencing other parameters such as extracellular and intracellular pH, it has an effect on different metabolic pathways which are involved in cell growth or in product formation and quality.

Download part 1 of our Dissolved CO? White Paper Series to learn how implementing real-time control of carbon dioxide can impact productivity at R&D and production scale bioreactors:

https://www.hamiltoncompany.com/process-analytics/dissolved-co2-pco2-bioreactor?