Nano-Cyte^® Brochure

What is Nano-Cyte®?
The Nano-Cyte® single molecule imaging system eliminates the microscope drift that limits advanced fluorescence imaging methods. With Nano-Cyte® you no longer need to be concerned with temperature gradients, sample drift, and microscope drift. Unprecedented stability in the nanometer regime allows long term experiments as never before.

The Nano-Cyte® works by using the image of fluorescent fiduciary references, sparsely distributed within the sample, to localize these emitters in all three dimensions. The Nano-Cyte® uses this 3D localization information to provide active position adjustments to the sample, thus eliminating drift in the experiment.

Nano-Cyte® is the complete stabilization and image acquisition instrument for advanced fluorescence microscopy. Our integrated approach to 3D stabilization yields image stability up to 3nm in X,Y and Z axes. Nano-Cyte® has proven stability over days and is a unique offering that promises to revolutionize advanced microscopy methods.

Features

• 3D stabilization up to 3 nanometers
• Active positional control over days
• Corrects for temperature gradients and drift
• Simultaneous image acquisition and stabilization
• Particle localization analysis
• Particle position rendering

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Mad City Labs, Inc
Mad City Labs, Inc has been a leading manufacturer of flexure based piezo nanopositioning systems capable of sub-nanometer positioning resolution since 1998. Our piezo nanopositioning product line covers the entire spectrum of piezo nanopositioning capabilities while maintaining a leadership role in multi-axis stages for high speed optical microscopy imaging. Mad City Labs engineers use 3D CAD and finite element analysis to produce piezo nanopositioners which combine long ranges of motion with exceptional linearity, orthogonality, and stability. Our in-house CNC machining centers and wire EDMs provide complete control of mechanical assembly production and allow Mad City Labs to design and fabricate custom systems with minimal engineering costs and short lead times. We deliver the tools for nanotechnology in 30 to 45 days and provide the highest level of customer service and satisfaction in the industry. We provide innovative and practical solutions for today’s demanding biotechnology and nanotechnology applications. Most Mad City Labs piezo nanopositioners can be controlled by our high speed USB 2.0 interface. Applications for nanopositioners include super resolution microscopy, high speed confocal imaging, AFM, NSOM, scanning probe microscopy, fiber positioning, single molecule spectroscopy, single molecule/particle tracking, high resolution optical alignment, SR optical microscopy, sub-diffraction limit microscopy, nanoscopy and lithography.