Item 1
Plasma Processes and Polymers
2, No.8, 11th Oct.2005, p. 605 11
FABRICATION OF BIOACTIVE SURFACES BY PLASMA POLYMERIZATION TECHNIQUES USING A NOVEL ACRYLATE-DERIVED MONOMER
Francesch L; Garreta E; Balcells M; Edelman E R; Borros S
Ramon Llull, University; Harvard, University;
Massachusetts Institute of Technology; Boston, Brigham & Women's Hospital; Harvard Medical School

A polymer was synthesised from pentafluorophenyl methacrylate (PFM) and was deposited on silicon wafers by plasma-enhanced chemical vapour deposition. The optimal plasma polymerisation parameters for the PFM monomer and its copolymerisation with crosslinking agents, i.e. 1,7-octadiene and 1,4-butanediol divinyl ether comonomers, were established. All the polymer coatings obtained left the labile pentafluorophenyl group on the surface, enabling a rapid reaction with an amino-terminated biotin ligand and allowing layer-by-layer assembly of biotin-streptavidin. In addition, the deposited polymer layers showed an extremely flat morphology with a nanoscale average roughness. This approach provided an easy method of obtaining functionalised surfaces that could enhance and control the biocompatibility of bulk materials. It was demonstrated that by combining the versatility of plasma polymerisation processes, via simple monomers and reaction conditions, with biological platforms that enabled targeting of cell adhesion, the ultimate goal of controlling cell function through structured surfaces for their application in tissue engineering was brought closer. 29 refs.

EUROPEAN COMMUNITY; EUROPEAN UNION; SPAIN; USA; WESTERN EUROPE

Accession no.956291

Item 2
Journal of Adhesion Science and Technology
18, No.12, 2004, p. 1465 81
ADHESION OF COPPER TO POLY(TETRAFLUOROETHYLENE-CO-HEXAFLUOROPROPYLENE) (FEP) SURFACES MODIFIED BY VACUUM UV PHOTO-OXIDATION DOWNSTREAM FROM AR MICROWAVE PLASMA
Dasilva W;