TABLE OF CONTENTS Kawai and co-workers [173] determined the composition of butyl acrylate ethyl acrylate copolymers with a narrow chemical composition distribution by 1H NMR spectroscopy and the components of the copolymers separated by normal and reversed phase high-performance liquid chromatography (HPLC) using crosslinked acrylamide and styrene beads. Samples containing higher butyl acrylate content eluted faster with normal phase HPLC while the opposite occurred with reversed phase HPLC, indicating that butyl acrylate is less polar than ethyl acrylate.
Kase and co-workers [174] investigated an isocyanate prepolymer composition using HPLC and field desorption MS.
Sandra and co-workers [175] present an overview of the use of MS as a detection system for liquid chromatography. Enjalbal and co-workers [176] characterised soluble polymer-supported organic compounds by liquid chromatography/electroscopy ionisation mass spectrometry. Julian and Domingo [177] have pointed out that the coupling of spectroscopic instruments to liquid chromatography instruments has not been as rapidly developed or successful as techniques such as GC-MS and GC-IR spectroscopy. A new liquid chromatography infrared spectroscopy interface is described which promises to be a successful marriage of these techniques. Although it does not provide a real-time analysis, it has the advantages of total solvent removal before infrared analysis, analysis of the total liquid chromatography eluate as opposed to incremental fractions, and the ability to produce infrared spectra at high signal-to-noise ratios.
