Plate 1 Probability of n molecules of protein N at time t, for the model presented in chapter 2 with [Cro2] = [Repressor2] = 0. Color represents probability. (See chapter 2.)

Plate 2 Probability of n molecules of protein N at time t, for the model presented in chapter 2 with [Cro2] = 50 nM, [Repressor2] = 10 nM. Color represents probability. (See chapter 2.)

Plate 3 (opposite, top) The pattern of Endo16 expression during S. purpuratus embryonic growth. Numbers of hours post fertilization are shown at the top left of each figure. Side views are shown. Cells labeled brown indicate the daughters of a single macromere; cells stained blue are those expressing Endo16. Note Endo16 expression is always confined to a fraction of the macromere descendants. Adapted from Ransick and Davidson (1995). (See chapter 3.)

Plate 4 (opposite, middle) Summary of Endo16 cis-regulatory organization. The 2300-base pair cis-domain of Endo16 comprises 31 protein binding sites (red boxes on horizontal black line denoting DNA) organized into six modular subregions labeled A G at the top of the figure. The boundaries of the modules are delineated by the thin vertical lines incident on the DNA. Bp represents the basal promoter and the region to its right, marked by the bold arrow, marks the coding region of the gene. The large colored symbols above the DNA line indicate the unique binding sites within each module. The...