Technical Articles

Baker has published these technical articles:

(Education and Career Services)
From this Article:
Measuring oxygen consumption by cells provides ample information on how cells are doing. It is in the core of mitochondrial function, metabolism and carbon cycling. Cells take up oxygen that then...
(Lab Safety)
From this Article:
SCI-tive is a physiologically relevant, protected and controlled environment workstation for researchers that need a bit more space that can be, if desired, expanded to a multi-chamber GMP-level...
(Lab Safety)
From this Article:
For Class II Type A2 "Recirculating" Biosafety Cabinets regardless of whether they are connected to a building exhaust system or not....
(Medical)
From this Article:
Stem cells reside in niches that have much lower oxygen concentration than many other parts of the body. Hypoxia maintains the niche where stem cells stay in optimal condition that benefits the...
(Optical Components)
From this Article:
The Baker Company has partnered with Lucid Scientific, a manufacturer of the most sensitive and accurate optical oxygen sensors available, to distribute its novel product line in North America....
(Education and Training)
From this Article:
I've spent the last three years looking for a better way to recreate and observe cell responses in the laboratory. This has been the focus for my PhD, 'Defining an in vitro model of normoxia and its...
(Uncategorized)
From this Article:
As a director of Baker Ruskinn, I help lead the field in developing technologies that deliver affordable, real-time information about cell behaviour in abnormal physiology....
(Medical)
From this Article:
ABSA International is pleased to announce a searchable laboratory acquired infection (LAI) database of peer-reviewed journal articles....
(Lab Safety)
From this Article:
Biosafety cabinets at Baylor Institute for Immunology Research provide safety and reliability....
(Enclosures)
From this Article:
When selecting which biosafety cabinet is right for you, price is almost always a top consideration. While sticker price seems like the most pertinent cost data, you need to consider the total cost of...
(Lab Safety)
From this Article:
Most microbiology lab managers and PIs purchase jars to run experiments, rather than purchase an anaerobic workstation. The up-front cost to use jars is low compared with a workstation, and since the...
(Environmental Test Equipment)
From this Article:
Cost Differential (Bugbox vs. Jars)...
(Lab Equipment)
From this Article:
With so much at stake, it is vital to understand the level of protection that is needed to keep you safe....
(Lab Thermal Processing)
From this Article:
Many terms are used (often interchangeably) to describe the removal of biohazards. In the lab, we often say that a work surface or piece of equipment needs to be "decontaminated." "Sterile" items need...
(Education and Career Services)
From this Article:
Baker, the developers of the Biosafety Cabinet (BSC) and pillar for biosafety containment and clean air, acquired the physiological oxygen workstation creators, Ruskinn. With the release of the new...
(Environmental Test Equipment)
From this Article:
Plants grow in a dynamic environment and often encounter low oxygen conditions, for instance flooding. For them, like for all other species, sensing and reacting to the changed environment in a timely...
(Lab Safety)
From this Article:
Biosafety cabinets safeguard scientists as they diagnose the world's most deadly diseases. Ethiopia is reducing its costs and increasing its independence through training a group of engineers to...
(Lab Equipment)
From this Article:
Prof. Nicholas Forsyth, Associate Director of the Institute of Science and Technology at Keele University in the UK, discusses how the use of a hypoxia workstation helped his team to develop a more...
(Air Quality)
From this Article:
It is common knowledge that to have a clean environment inside a biosafety cabinet or clean bench, you have to have HEPA-filtered air. Presumably, the filter removes all contaminants, but does it...
(Lab Equipment)
From this Article:
Prof. Nicholas Forsyth, Associate Director of the Institute of Science and Technology at Keele University in the UK, discusses how the use of a media conditioning system helped his team improve stem...
(Gas Sensing)
From this Article:
The Concept Series Workstations have been recently remodelled. This report details the oxygen concentration throughout the work area within the workstation in anaerobic mode to ensure proper...
(Air Quality)
From this Article:
The Invivo2 / Concept / Concept-M Series Workstations have been recently remodelled, and now include a standard HEPA filter. This report details the HEPA filter testing and results for the common body...
(Temperature Sensing)
From this Article:
The Invivo2 / Concept / Concept-M Series Workstations have been recently remodelled. This report details the temperature uniformity throughout the work area within the workstation to ensure proper...
(Lab Safety)
From this Article:
NSF/ANSI 49 - 2016 Annex E "Biosafety Cabinet Selection, Installation, Use, Lifespan and Decommissioning...
(Medical)
From this Article:
How to better mimic cell physiology...
(Education and Career Services)
From this Article:
Most laboratory techniques utilize biosafety cabinets (BSCs) in order to provide contamination control of the experiments. BSCs depend on airflow and HEPA filters to remove contaminants from the...
(Lab Safety)
From this Article:
Dual-sided biosafety cabinet makes Jackson Laboratory more efficient....
(Lab Safety)
From this Article:
Biosafety Cabinet at the University of Iowa Laryngeal Molecular and Cell Biology Laboratory provides safe and energy-efficient environment...
(Lab Equipment)
From this Article:
Accurately simulating blood vessel microenvironment....
(Medical)
From this Article:
It's funny how things can get labeled with certain words that don't completely make sense. Misnomers are all over the place. Jellyfish aren't fish. Rhode Island isn't an island. Koala bears are...
(Microscopy)
From this Article:
A hot new concept coming through the world of cell culture is the notion that the current "gold standard" method of culturing cells is good, but could be better. The use of incubators and separate...
(Lab Safety)
From this Article:
Biosafety cabinets at the University of Southern Maine's Wise Laboratory are at the heart of high-impact toxicology research...
(Enclosures)
From this Article:
When working with cells that require a low-oxygen atmosphere to thrive, it is important to create a continuously controlled environment to avoid oxidative stress. Shocking cells by removing them from...
(Lab Safety)
From this Article:
Intracellular O2 is a key regulator of NO signaling, yet most invitro studies are conducted in atmospheric O2 levels, hyperoxic with respect to the physiologic milieu. We investigated NO signaling in...
(Lab Safety)
From this Article:
BSC MythBusters: Does Heat Really Affect My Protection? Watch the presentation given by Kara Held, Ph.D., Baker's Science Director, at the 2018 ABSA Scientific Session on Wednesday, 10/10/2018. In her...
(Medical)
From this Article:
The aim of this study was to determine the growth rate of human dental pulp stem cells (hDPSCs) under physiological oxygen tension (3%), and to investigate the cell signaling pathways underlying...
(Microscopy)
From this Article:
The company, Mesoblast are currently working to show that cell therapy is effective in patients with acute respiratory distress syndrome (ARDS) caused by the SARS-CoV-2 virus....
(Medical)
From this Article:
The present study provides the first detailed characterization of Nrf2-regulated redox signaling in human primary venous and arterial EC adapted long-term (5 days-2 weeks) to physiological oxygen (5%...
(Lab Safety)
From this Article:
According to the Institute of Neurodegenerative Diseases website, the United States is facing an epidemic of dementia, with Alzheimer's disease affecting five million Americans. Close to half of the...
(Lab Safety)
From this Article:
There are a lot of rules, "guidelines", rumors, and myths for using a Biosafety Cabinet. * Which are true? * Which are not? * WHY?...
(Medical)
From this Article:
UV lamps in BSCs use short-wave UV-C (254nm) irradiation to kill microorganisms by disrupting their DNA. Download the Baker MythBuster presentation!...
(Lab Safety)
From this Article:
ABSA 2019 MythBuster presentation. Watch Baker's Science Director, Kara Held Ph.D. present her latest findings!...
(Material Handling Equipment)
From this Article:
Work conducted in Biosafety Cabinets (BSCs) is a common sight in many laboratories worldwide, but some misconceptions about their capabilities sometimes arise. A BSC used for storage of materials or...
(Medical)
From this Article:
Physiologists have long recognized that what are often referred to as hypoxia and normoxia in cell culture studies are actually normoxia and hyperoxia, except for cells from the few tissues that are...
(Medical)
From this Article:
Here's a handy chart of commonly used cleaners and their compatibility with 304 and 316 Stainless Steel....
(Medical)
From this Article:
This review aims to readdress the conditions in which all mammalian cells should be cultured, with the aim of more effective translation of invitroscience into potentially life-saving therapies....
(Medical)
From this Article:
Researchers at Wake Forest School of Medicine say that they have identified a set of new genetic bio markers. These markers could potentially lead to new personalized treatments for lung cancer....
(Medical)
From this Article:
HOW HEPAs WORK...
(Medical)
From this Article:
Heat sources in a Biosafety Cabinet Compromise Experimental and User Protection. Several heat sources were evaluated in two sizes of BSC, using smoke for airflow visualization, particle counting for...
(Education and Career Services)
From this Article:
Baker's Director of Scientific Applications, Krista Rantanen Ph.D. hosts the second interview of the series! The Unexpected Questions with Dr. Ox interviews leading scientists around the world....
(Lab Safety)
From this Article:
Restarting your workstation after an extended period of time...
(Lab Safety)
From this Article:
A Biosafety Cabinet (BSC) is a ventilated enclosure that is an essential piece of lab equipment for many procedures. They are the primary source of contamination removal and prevention, and are...
(Medical)
From this Article:
Keeping a contamination free environment in the laboratory has commonly been achieved by one of two ways: a flame or a biosafety cabinet (BSC). However, it has been frequently observed that the two...
(Lab Safety)
From this Article:
Providing Additional Clean Room Technology...
(Lab Safety)
From this Article:
Primary Containment for most biological laboratories starts with the Biosafety Cabinet (BSC). Download the latest white paper on multiple users in a BSC!...
(Material Handling Equipment)
From this Article:
Westerly Hospital recently unveiled their new $4 million pharmacy facility. Can you spot Baker's BioChemGARD cabinets in this article?...
(Environmental Test Equipment)
From this Article:
Scientists at Huazhong University of Science and Technology have developed a nanophotosynthetic therapy (NPT) platform that they hope could one day help to protect against brain damage in stroke...
(Education and Career Services)
From this Article:
Scientists at The University of New South Wales have discovered that in order to fight pancreatic cancer more effectively, cancer cells and their collaborators need to be attacked....
(Medical)
From this Article:
HIF-1 is the key transcription factor responsible for inducing PRKAR2B expression in prostate cancer...
(Microscopy)
From this Article:
In CRUK, Manchester, UK, the group of Dr. Debayan Mukherjee does in vitro research investigating the effects of radiation and hypoxia on the immune contexture. They use CondoCell® to transport...
(Medical)
From this Article:
To date, in vitro studies assessing the pulmonary toxicity of inhaled particles have provided poor correlation with in vivo results. We explored whether this discrepancy re?ected cellular adaptations...
(Education and Career Services)
From this Article:
A study has shown that low doses of radiation could help to improve the quality of life for patients living with Alzheimer's disease. Further studies are now underway to determine the optimal range...
(Lab Safety)
From this Article:
Unregulated increases in cellular Ca2+ homeostasis are a hallmark of pathophysiological conditions and a key trigger of cell death. Endothelial cells cultured under physiologic O2 conditions (5% O2)...
(Lab Safety)
From this Article:
Restarting your workstation after an extended period of time...
(Education and Career Services)
From this Article:
With COVID-19 dominating the science industry for the last year, our mission to #SupportScience has never been more important...
(Medical)
From this Article:
As vaccines are rolled out in many countries, the hope for a new normality could soon be on the horizon....
(Medical)
From this Article:
Last month, the FDA approved Abecma as the first B-cell maturation antigen (BCMA)- directed chimeric antigen receptor T-cell immunotherapy for patients with relapsed or refractory multiple myeloma....
(Medical)
From this Article:
TCR2 Therapeutics Inc., a clinical stage-cell therapy company with a pipeline of novel T cell therapies for patients suffering from cancer is expanding to a facility in Rockville, Maryland. The...
(Medical)
From this Article:
Here we determined that DNA is captured by a HEPA filter at the same efficiency as the filter is rated and discovered DNA cannot be dislodged from a HEPA filter....
(Education and Career Services)
From this Article:
New and extensive research completed by the University of Bologna revealed that there are 6 strains of COVID-19. The first to appear was the L strain, followed by S, V and G. To date, the G strain is...
(Medical)
From this Article:
It has been highlighted that Ebselen is able to block enzymes that the new COVID-19 needs to invade and replicate within healthy host cells. The drug is currently used to treat Bipolar Disorder and...
(Medical)
From this Article:
Two potential vaccines will take part in an adaptive Phase I/II human clinical study. Two candidates including VBI-2901, a trivalent pan-coronavirus candidate expresses the SARS-CoV-2 and MERS CoV...
(Lab Safety)
From this Article:
Volatile chemicals, while typically used in a fume hood, may sometimes be used in conjunction with biological experiments which often require the use of a biosafety cabinet (BSC). While a 100%...
(Lab Safety)
From this Article:
Two methods of enclosing the biosafety cabinet (BSC) may be employed: tenting (wrapping the BSC in plastic sheeting) or taping (taping around the viewscreen with the aid of a fabricated front panel...
(Medical)
From this Article:
Hypoxia, a condition of low oxygen availability, is a hallmark of tumour microenvironment and promotes cancer progression and resistance to therapy....
(Medical)
From this Article:
Retinal neovascularization (RNV) is a type of serious vision-threating disease, commonly induced by hypoxia of ischemic retinopathy, which happens in various ocular diseases including diabetic...
(Medical)
From this Article:
Prostate cancer deposits exist within a hypoxic environment...
(Lab Safety)
From this Article:
The purpose of this study was to investigate the distribution and specify the transmission and cross-contamination of Clostridium perfringens (C. perfringens) in the beef slaughtering and butchering...
(Education and Training)
From this Article:
March is Women's History Month! The Baker Company is marking this event by celebrating some of the women who have made significant contributions to science in the past...