Technical Articles
Baker has published these technical articles:
(Medical)
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Current cell culture methods involve perpetual incubation in a warm environment. Incubators are the most prevalent tool; however, workstations are becoming more popular....
(Lab Safety)
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Work conducted in Biosafety Cabinets (BSCs) is a common sight in many laboratories worldwide, but some misconceptions about their capabilities sometimes arise....
(Optical Components)
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The Baker Company has partnered with Lucid Scientific, a manufacturer of the most sensitive and accurate optical oxygen sensors available, to distribute its novel product line in North America....
(Enclosures)
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When selecting which biosafety cabinet is right for you, price is almost always a top consideration. While sticker price seems like the most pertinent cost data, you need to consider the total cost of...
(Environmental Test Equipment)
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Cost Differential (Bugbox vs. Jars)...
(Lab Thermal Processing)
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Many terms are used (often interchangeably) to describe the removal of biohazards. In the lab, we often say that a work surface or piece of equipment needs to be "decontaminated." "Sterile" items need...
(Environmental Test Equipment)
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Plants grow in a dynamic environment and often encounter low oxygen conditions, for instance flooding. For them, like for all other species, sensing and reacting to the changed environment in a timely...
(Gas Sensing)
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The Concept Series Workstations have been recently remodelled. This report details the oxygen concentration throughout the work area within the workstation in anaerobic mode to ensure proper...
(Air Quality)
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The Invivo2 / Concept / Concept-M Series Workstations have been recently remodelled, and now include a standard HEPA filter. This report details the HEPA filter testing and results for the common body...
(Temperature Sensing)
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The Invivo2 / Concept / Concept-M Series Workstations have been recently remodelled. This report details the temperature uniformity throughout the work area within the workstation to ensure proper...
(Enclosures)
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When working with cells that require a low-oxygen atmosphere to thrive, it is important to create a continuously controlled environment to avoid oxidative stress. Shocking cells by removing them from...
(Lab Safety)
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According to the Institute of Neurodegenerative Diseases website, the United States is facing an epidemic of dementia, with Alzheimer's disease affecting five million Americans. Close to half of the...
(Lab Safety)
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Is UV Light An Effective Disinfectant In Your BSC?...
(Medical)
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Researchers at Wake Forest School of Medicine say that they have identified a set of new genetic bio markers.
These markers could potentially lead to new personalized treatments for lung cancer....
(Material Handling Equipment)
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Westerly Hospital recently unveiled their new $4 million pharmacy facility. Can you spot Baker's BioChemGARD cabinets in this article?...
(Environmental Test Equipment)
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Scientists at Huazhong University of Science and Technology have developed a nanophotosynthetic therapy (NPT) platform that they hope could one day help to protect against brain damage in stroke...
(Education and Career Services)
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Scientists at The University of New South Wales have discovered that in order to fight pancreatic cancer more effectively, cancer cells and their collaborators need to be attacked....
(Medical)
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HIF-1 is the key transcription factor responsible for inducing PRKAR2B expression in prostate cancer...
(Education and Career Services)
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A study has shown that low doses of radiation could help to improve the quality of life for patients living with Alzheimer's disease.
Further studies are now underway to determine the optimal range...
(Education and Career Services)
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With COVID-19 dominating the science industry for the last year, our mission to #SupportScience has never been more important...
(Medical)
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As vaccines are rolled out in many countries, the hope for a new normality could soon be on the horizon....
(Air Quality)
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Kara's research examines exactly how much DNA can penetrate a HEPA filter....
(Education and Career Services)
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New and extensive research completed by the University of Bologna revealed that there are 6 strains of COVID-19. The first to appear was the L strain, followed by S, V and G. To date, the G strain is...
(Medical)
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It has been highlighted that Ebselen is able to block enzymes that the new COVID-19 needs to invade and replicate within healthy host cells. The drug is currently used to treat Bipolar Disorder and...
(Medical)
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Two potential vaccines will take part in an adaptive Phase I/II human clinical study. Two candidates including VBI-2901, a trivalent pan-coronavirus candidate expresses the SARS-CoV-2 and MERS CoV...
(Lab Safety)
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Volatile chemicals, while typically used in a fume hood, may sometimes be used in conjunction with biological experiments which often require the use of a biosafety cabinet (BSC). While a 100%...
(Air Quality)
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Providing a clean air environment for cultures during incubation is critical to preventing contamination. Some manufacturers equip their incubators with a HEPA filter and claim to provide ISO Class 5...
(Medical)
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Our SCI-tive physoxia workstation supported research into the impact of space microgravity on neural stem cells? Read about Dr. Araceli Espinosa-Jeffrey's incredible project...
(Lab Safety)
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The inability to use the outer ring of wells in a microtiter or multiwell cell culture plate, commonly known as the Edge Effect, has been plaguing researchers for too long. This phenomenon is due to...
(Lab Equipment)
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Two methods of enclosing the biosafety cabinet (BSC) may be employed: tenting (wrapping the BSC in plastic sheeting) or taping (taping around the viewscreen with the aid of a fabricated front panel...
(Lab Safety)
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Incubators are standard laboratory equipment but are constantly prone to internal contamination by bacteria, water molds, fungus and mycoplasma and require a simple yet effective method for...
(Lab Safety)
From this Article:
The inability to use the outer ring of wells in a microtiter or multiwell cell culture plate, commonly known as the Edge Effect, has been plaguing researchers for too long. This phenomenon is due to...
(Medical)
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Recently, many more genes are being shown to be direct targets of HIF, especially in cell type specific manners. This opens a huge door for new areas of research that just need to start culturing...
(Medical)
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Hypoxia, a condition of low oxygen availability, is a hallmark of tumour microenvironment and promotes cancer progression and resistance to therapy....
(Medical)
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Retinal neovascularization (RNV) is a type of serious vision-threating disease, commonly induced by hypoxia of ischemic retinopathy, which happens in various ocular diseases including diabetic...
(Lab Safety)
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Why low oxygen study conditions make a difference...
(Medical)
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Prostate cancer deposits exist within a hypoxic environment...
(Lab Safety)
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The purpose of this study was to investigate the distribution and specify the transmission and cross-contamination of Clostridium perfringens (C. perfringens) in the beef slaughtering and butchering...
(Education and Training)
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March is Women's History Month! The Baker Company is marking this event by celebrating some of the women who have made significant contributions to science in the past...
(Medical)
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There is increasing evidence that antimicrobial resistance in BFG is linked to adverse outcomes...
(Lab Safety)
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One of the most important considerations is BSC placement, and unfortunately there is a lot of differing guidelines out there. Kara Held, Ph.D., from The Baker Company, challenged the layout criteria...
(Lab Safety)
From this Article:
Incubators are standard laboratory equipment but are constantly prone to internal contamination by bacteria, water molds, fungus and mycoplasma and require a simple yet effective method for...
(Medical)
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Here, we investigated the diffusive flux of CH4 and its stable carbon isotope signature (d13C-CH4) along the river-estuary continuum of the Yangtze River....
(Medical)
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Previous studies have suggested that the expression of the HIF1 subunit, HIF1a, is elevated in HBV-infected hepatocytes; however, whether HIF1 activity affects the HBV lifecycle has not been fully...
(Medical)
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Here we aimed to investigate the effects of metformin on osteoblast differentiation and osteoclast formation in cultured cells and rat apical periodontitis....
(Medical)
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Oxygen is a fundamental factor for most life forms. For life science researchers, O2 is an electron acceptor, a highly reactive molecule that affects every single event and reaction in biology....
(Environmental Test Equipment)
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Stem Cells Respond Differently to Oxygen Levels...
(Lab Safety)
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The Role of Standards in Biosafety Cabinet Design...
(Environmental Test Equipment)
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A bit about Biosafety Cabinets...
(Lab Safety)
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Understanding Biosafety Cabinets...
(Lab Safety)
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This document explains why UV light provides inconsistent disinfection inside biosafety cabinets and how chemical compatibility varies by stainless-steel grade. It outlines realistic UV limitations,...
(Lab Safety)
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Chemical Disinfectants: Compatible Doesn't Mean Safe...
(Lab Safety)
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When Clostridium research is performed without the proper setup, outcomes can be compromised in ways that affect scientific validity, laboratory safety, and resource efficiency:...
(Environmental Test Equipment)
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In a Lab Manager webinar, we discussed in depth which types of CO2 incubator humidity control technologies to look for to provide optimal relative humidity and condensation control for cell culture...
(Air Quality)
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Does Your CO2 Incubator Actively Control Humidity?...
(Lab Safety)
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There are a lot of rules, “guidelines”, rumors, and myths for using a Biosafety Cabinet. Which are true? Which are not?...
(Lab Safety)
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The Four Buckets of Ventilation Equipment...
(Air Quality)
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The Importance of Air Cleanliness in CO2 Incubators...
(Lab Safety)
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The use of three-dimensional (3D) printing has found application in the tissue and cell culture arena....
(Lab Safety)
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Keeping a contamination free environment in the laboratory has commonly been achieved by one of two ways: a flame or a biosafety cabinet (BSC). However, it has been frequently observed that the two...
(Lab Safety)
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What is a Clean Bench?...
(Medical)
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Epigenetics Meets RNA Splicing Under Hypoxia...
(Air Quality)
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Why Air Quality Matters in Animal Transfer...
(Lab Equipment)
From this Article:
A common concern with all-in-one workstations, also known as incubated workstations or incubated glove boxes, is that excessive vibration could negatively impact cell growth and adhesion. This study...
(Lab Safety)
From this Article:
There are known commonly performed actions within BSC operation that may compromise BSC containment....
(Air Quality)
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In the laboratory, when animals are transferred or when their cages are cleaned, it is important to use the right equipment to protect both the animal and the researcher from exposure to contaminants....
(Environmental Test Equipment)
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Understanding Biosafety Cabinets...
(Lab Equipment)
From this Article:
Understanding Physoxic Cell Culture Conditions...
(Lab Safety)
From this Article:
The fundamentals for a good research model not only includes the environment under which cells are contained, but also the media in which cells are grown....
(Environmental Test Equipment)
From this Article:
The operational air flow balance recommended by the Class II biological safety cabinet (BSC) manufacturer is called the nominal setpoint. Few, if any, BSCs actually operate at nominal setpoint under...
(Environmental Test Equipment)
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Biological safety cabinets, essential in laboratories around the world, are the cornerstone of safety when working with hazardous biological materials...
(Lab Safety)
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What Is Airflow Balance in a BSC?...
(Environmental Test Equipment)
From this Article:
What is a Biosafety Cabinet?...
(Environmental Test Equipment)
From this Article:
Why Low Oxygen Matters in Cell Culture...
(Medical)
From this Article:
Oxygen in the Body vs Oxygen in the Incubator...
(Lab Safety)
From this Article:
Due to the highly variable results from location to location, and between burner types, using a heat source within a BSC cannot be recommended. There are too many instances where Containment may be...
(Lab Safety)
From this Article:
Oxygen; nitric oxide; hypoxia; angiogenesis; immune response; synaptic communication; cancer...