Technical Articles
Baker has published these technical articles:
(Medical)
From this Article:
Heat sources in a Biosafety Cabinet Compromise Experimental and User Protection. Several heat sources were evaluated in two sizes of BSC, using smoke for airflow visualization, particle counting for...
(Material Handling Equipment)
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Work conducted in Biosafety Cabinets (BSCs) is a common sight in many laboratories worldwide, but some misconceptions about their capabilities sometimes arise. A BSC used for storage of materials or...
(Education and Career Services)
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Measuring oxygen consumption by cells provides ample information on how cells are doing. It is in the core of mitochondrial function, metabolism and carbon cycling. Cells take up oxygen that then...
(Lab Safety)
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SCI-tive is a physiologically relevant, protected and controlled environment workstation for researchers that need a bit more space that can be, if desired, expanded to a multi-chamber GMP-level...
(Lab Safety)
From this Article:
For Class II Type A2 "Recirculating" Biosafety Cabinets regardless of whether they are connected to a building exhaust system or not....
(Medical)
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Stem cells reside in niches that have much lower oxygen concentration than many other parts of the body. Hypoxia maintains the niche where stem cells stay in optimal condition that benefits the...
(Optical Components)
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The Baker Company has partnered with Lucid Scientific, a manufacturer of the most sensitive and accurate optical oxygen sensors available, to distribute its novel product line in North America....
(Uncategorized)
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As a director of Baker Ruskinn, I help lead the field in developing technologies that deliver affordable, real-time information about cell behaviour in abnormal physiology....
(Enclosures)
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When selecting which biosafety cabinet is right for you, price is almost always a top consideration. While sticker price seems like the most pertinent cost data, you need to consider the total cost of...
(Environmental Test Equipment)
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Cost Differential (Bugbox vs. Jars)...
(Lab Thermal Processing)
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Many terms are used (often interchangeably) to describe the removal of biohazards. In the lab, we often say that a work surface or piece of equipment needs to be "decontaminated." "Sterile" items need...
(Education and Career Services)
From this Article:
Baker, the developers of the Biosafety Cabinet (BSC) and pillar for biosafety containment and clean air, acquired the physiological oxygen workstation creators, Ruskinn. With the release of the new...
(Environmental Test Equipment)
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Plants grow in a dynamic environment and often encounter low oxygen conditions, for instance flooding. For them, like for all other species, sensing and reacting to the changed environment in a timely...
(Lab Equipment)
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Prof. Nicholas Forsyth, Associate Director of the Institute of Science and Technology at Keele University in the UK, discusses how the use of a hypoxia workstation helped his team to develop a more...
(Air Quality)
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It is common knowledge that to have a clean environment inside a biosafety cabinet or clean bench, you have to have HEPA-filtered air. Presumably, the filter removes all contaminants, but does it...
(Lab Equipment)
From this Article:
Prof. Nicholas Forsyth, Associate Director of the Institute of Science and Technology at Keele University in the UK, discusses how the use of a media conditioning system helped his team improve stem...
(Gas Sensing)
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The Concept Series Workstations have been recently remodelled. This report details the oxygen concentration throughout the work area within the workstation in anaerobic mode to ensure proper...
(Air Quality)
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The Invivo2 / Concept / Concept-M Series Workstations have been recently remodelled, and now include a standard HEPA filter. This report details the HEPA filter testing and results for the common body...
(Temperature Sensing)
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The Invivo2 / Concept / Concept-M Series Workstations have been recently remodelled. This report details the temperature uniformity throughout the work area within the workstation to ensure proper...
(Education and Career Services)
From this Article:
Most laboratory techniques utilize biosafety cabinets (BSCs) in order to provide contamination control of the experiments. BSCs depend on airflow and HEPA filters to remove contaminants from the...
(Microscopy)
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A hot new concept coming through the world of cell culture is the notion that the current "gold standard" method of culturing cells is good, but could be better. The use of incubators and separate...
(Enclosures)
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When working with cells that require a low-oxygen atmosphere to thrive, it is important to create a continuously controlled environment to avoid oxidative stress. Shocking cells by removing them from...
(Microscopy)
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The company, Mesoblast are currently working to show that cell therapy is effective in patients with acute respiratory distress syndrome (ARDS) caused by the SARS-CoV-2 virus....
(Lab Safety)
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According to the Institute of Neurodegenerative Diseases website, the United States is facing an epidemic of dementia, with Alzheimer's disease affecting five million Americans. Close to half of the...
(Lab Safety)
From this Article:
There are a lot of rules, "guidelines", rumors, and myths for using a Biosafety Cabinet.
* Which are true?
* Which are not?
* WHY?...
(Medical)
From this Article:
UV lamps in BSCs use short-wave UV-C (254nm) irradiation to kill microorganisms by disrupting their DNA. Download the Baker MythBuster presentation!...
(Medical)
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Here's a handy chart of commonly used cleaners and their compatibility with 304 and 316 Stainless Steel....
(Medical)
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This review aims to readdress the conditions in which all mammalian cells should be cultured, with the aim of more effective translation of invitroscience into potentially life-saving therapies....
(Medical)
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Researchers at Wake Forest School of Medicine say that they have identified a set of new genetic bio markers.
These markers could potentially lead to new personalized treatments for lung cancer....
(Medical)
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HOW HEPAs WORK...
(Lab Safety)
From this Article:
Restarting your workstation after an extended period of time...
(Medical)
From this Article:
Keeping a contamination free environment in the laboratory has commonly been achieved by one of two ways: a flame or a biosafety cabinet (BSC). However, it has been frequently observed that the two...
(Lab Safety)
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Providing Additional Clean Room Technology...
(Lab Safety)
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Primary Containment for most biological laboratories starts with the Biosafety Cabinet (BSC). Download the latest white paper on multiple users in a BSC!...
(Material Handling Equipment)
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Westerly Hospital recently unveiled their new $4 million pharmacy facility. Can you spot Baker's BioChemGARD cabinets in this article?...
(Environmental Test Equipment)
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Scientists at Huazhong University of Science and Technology have developed a nanophotosynthetic therapy (NPT) platform that they hope could one day help to protect against brain damage in stroke...
(Education and Career Services)
From this Article:
Scientists at The University of New South Wales have discovered that in order to fight pancreatic cancer more effectively, cancer cells and their collaborators need to be attacked....
(Medical)
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HIF-1 is the key transcription factor responsible for inducing PRKAR2B expression in prostate cancer...
(Microscopy)
From this Article:
In CRUK, Manchester, UK, the group of Dr.
Debayan Mukherjee does in vitro research
investigating the effects of radiation and
hypoxia on the immune contexture. They use
CondoCell® to transport...
(Medical)
From this Article:
To date, in vitro studies assessing the pulmonary toxicity of inhaled particles have provided poor correlation with in vivo results. We explored whether this discrepancy re?ected cellular adaptations...
(Education and Career Services)
From this Article:
A study has shown that low doses of radiation could help to improve the quality of life for patients living with Alzheimer's disease.
Further studies are now underway to determine the optimal range...
(Lab Safety)
From this Article:
Restarting your workstation after an extended period of time...
(Education and Career Services)
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With COVID-19 dominating the science industry for the last year, our mission to #SupportScience has never been more important...
(Medical)
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As vaccines are rolled out in many countries, the hope for a new normality could soon be on the horizon....
(Medical)
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Last month, the FDA approved Abecma as the first B-cell maturation antigen (BCMA)- directed chimeric antigen receptor T-cell immunotherapy for patients with relapsed or refractory multiple myeloma....
(Medical)
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TCR2 Therapeutics Inc., a clinical stage-cell therapy company with a pipeline of novel T cell therapies for patients suffering from cancer is expanding to a facility in Rockville, Maryland.
The...
(Medical)
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Here we determined that DNA is captured by a HEPA filter at the same efficiency as the filter is rated and discovered DNA cannot be dislodged from a HEPA filter....
(Education and Career Services)
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New and extensive research completed by the University of Bologna revealed that there are 6 strains of COVID-19. The first to appear was the L strain, followed by S, V and G. To date, the G strain is...
(Medical)
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It has been highlighted that Ebselen is able to block enzymes that the new COVID-19 needs to invade and replicate within healthy host cells. The drug is currently used to treat Bipolar Disorder and...
(Medical)
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Two potential vaccines will take part in an adaptive Phase I/II human clinical study. Two candidates including VBI-2901, a trivalent pan-coronavirus candidate expresses the SARS-CoV-2 and MERS CoV...
(Lab Safety)
From this Article:
Volatile chemicals, while typically used in a fume hood, may sometimes be used in conjunction with biological experiments which often require the use of a biosafety cabinet (BSC). While a 100%...
(Air Quality)
From this Article:
Providing a clean air environment for cultures during incubation is critical to preventing contamination. Some manufacturers equip their incubators with a HEPA filter and claim to provide ISO Class 5...
(Medical)
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Our SCI-tive physoxia workstation supported research into the impact of space microgravity on neural stem cells? Read about Dr. Araceli Espinosa-Jeffrey's incredible project...
(Lab Safety)
From this Article:
The inability to use the outer ring of wells in a microtiter or multiwell cell culture plate, commonly known as the Edge Effect, has been plaguing researchers for too long. This phenomenon is due to...
(Lab Equipment)
From this Article:
Two methods of enclosing the biosafety cabinet (BSC) may be employed: tenting (wrapping the BSC in plastic sheeting) or taping (taping around the viewscreen with the aid of a fabricated front panel...
(Lab Safety)
From this Article:
Incubators are standard laboratory equipment but are constantly prone to internal contamination by bacteria, water molds, fungus and mycoplasma and require a simple yet effective method for...
(Lab Safety)
From this Article:
The inability to use the outer ring of wells in a microtiter or multiwell cell culture plate, commonly known as the Edge Effect, has been plaguing researchers for too long. This phenomenon is due to...
(Lab Equipment)
From this Article:
The use of three-dimensional (3D) printing has found application in the tissue and cell culture arena....
(Medical)
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Recently, many more genes are being shown to be direct targets of HIF, especially in cell type specific manners. This opens a huge door for new areas of research that just need to start culturing...
(Medical)
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Hypoxia, a condition of low oxygen availability, is a hallmark of tumour microenvironment and promotes cancer progression and resistance to therapy....
(Medical)
From this Article:
Retinal neovascularization (RNV) is a type of serious vision-threating disease, commonly induced by hypoxia of ischemic retinopathy, which happens in various ocular diseases including diabetic...
(Lab Equipment)
From this Article:
Why low oxygen study conditions make a difference...
(Medical)
From this Article:
Prostate cancer deposits exist within a hypoxic environment...
(Lab Safety)
From this Article:
The purpose of this study was to investigate the distribution and specify the transmission and cross-contamination of Clostridium perfringens (C. perfringens) in the beef slaughtering and butchering...
(Lab Equipment)
From this Article:
Nitric oxide (NO) is a crucial signaling molecule in diverse biological processes. Dysregulation in NO signaling or its bioavailability is involved in various disorders. It is also sensitive to oxygen...
(Education and Training)
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March is Women's History Month! The Baker Company is marking this event by celebrating some of the women who have made significant contributions to science in the past...
(Medical)
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There is increasing evidence that antimicrobial resistance in BFG is linked to adverse outcomes...
(Medical)
From this Article:
Here, we investigated the diffusive flux of CH4 and its stable carbon isotope signature (d13C-CH4) along the river-estuary continuum of the Yangtze River....
(Medical)
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Previous studies have suggested that the expression of the HIF1 subunit, HIF1a, is elevated in HBV-infected hepatocytes; however, whether HIF1 activity affects the HBV lifecycle has not been fully...
(Medical)
From this Article:
Current cell culture methods involve perpetual incubation in a warm environment. Incubators are the most prevalent tool; however, workstations are becoming more popular....
(Medical)
From this Article:
Here we aimed to investigate the effects of metformin on osteoblast differentiation and osteoclast formation in cultured cells and rat apical periodontitis....
(Medical)
From this Article:
Oxygen is a fundamental factor for most life forms. For life science researchers, O2 is an electron acceptor, a highly reactive molecule that affects every single event and reaction in biology....