Microscopy Reference Materials

Description: In the world of advanced technology, some of the most critical components are also the least visible. Among them are ultra-precision optical mirrors-devices so accurate that their surface errors are ...

Description: Conventional microscope objectives are often not designed for the optical, mechanical, and material constraints imposed by quantum experiments. Challenges including long working distance requirements, ...

Description: This case study shows how custom objective lens design addressed simultaneous constraints involving long working distance, high numerical aperture, beam access, multi-wavelength performance, and ...

Description: Advanced optical design strategies can overcome traditional tradeoffs between long working distance and high numerical aperture. Through multi-element aberration balancing, infinity-corrected ...

Description: Journey through the history of scientific exploration, where light-sheet microscopy meets the complexities of life sciences. Over the past three decades, microscopic techniques have advanced ...

Description: p>Throughput Decoupling: Next-generation High-NA Multi-Mirror Array Objectives break the resolution-speed trade-off, reducing 12-inch wafer inspection to <8 minutes. Yield Economics: High-NA optics ...

Description: -Near-infrared (NIR) microscopy objectives (780-2500nm) are essential for "seeing through" opaque barriers. -By balancing high resolution with superior penetration, they enable deep-tissue biological ...

Description: -Fluorescence microscope objectives are specialized optical components designed to maximize light collection and resolution ($0.2\mu m$) while minimizing sample damage. -Key design factors include ...

Description: -The Infinite Conjugate Microscope Objective delivers superior optical flexibility, enabling modular imaging paths through its collimated beam design. -High numerical aperture, advanced aberration ...

Description: -Finite conjugate microscope objectives provide compact, stable, and cost-effective high-resolution imaging for industrial inspection, micro-nano machining, and portable diagnostic systems. -Their ...

Description: Many structural biology challenges are overcome with Transmission Electron Microscopy (TEM). Learn how TEM solves issues in molecular imaging and analysis. ...

Description: Daniel has extensive experience in performing failure analysis and routine product evaluation of components and assemblies for the Transportation sector. Scanning electron microscopy (SEM) is an ...

Description: Learn about radiation damage in cryo-electron microscopy, its impact on structural data, and strategies to minimize its effects in electron cryo-EM imaging. ...

Description: Learn the fundamentals of TEM sample preparation and how FIB-SEM technology enhances precision, reduces damage, and improves imaging for better research results. ...

Description: Key Takeaways - This case study examines the high NA infinity conjugate long working distance microscope objective, designed for optical tweezers and other precision applications. - With a 16 mm focal ...

Description: Photoacoustic Microscopy (PAM) is a high-resolution imaging technique that integrates optical and acoustic methods to overcome the optical diffusion limit. It enables in vivo imaging at depths of ...

Description: This series of electron microscope installation environment pictures, texts, and recommendations are based on practical experience gained from over a decade of site surveys and renovations. It holds a ...

Description: The Scanning Electron Microscope (SEM) is an important tool for observing micro-scale morphology and is widely used in fields such as materials science, biology, and environmental science. With the ...

Description: SEM (Scanning Electron Microscope) and TEM (Transmission Electron Microscope) are two common forms of electron microscopes. SEM uses Secondary Electrons (SE) and Back-scattered Electrons (BSE) to ...

Description: Common Issues: 1. Does the magnetic nature of a specimen affect SEM testing? 2. What are the effects of radioactive specimens on SEM testing? 3. Is specimen stability important for SEM testing? 4. Why ...

Description: The environment of an electron microscopy lab does not directly impact the electron microscope itself but rather affects the imaging quality and overall performance. During the operation of an ...

Description: When observing animal hair using a scanning electron microscope, a lot of microscopic information can be obtained. This information can not only help us determine the type of animal hair and ...

Description: High-performance lithium copper foil is one of the key materials for lithium-ion batteries and is closely related to battery performance. In materials science, the composition and microstructure ...

Description: When a metal breaks under external forces, it leaves behind two matching surfaces called "fracture surfaces" or "fracture faces." The shape and appearance of these surfaces contain important ...

Description: Infinite conjugate long working distance microscope objectives are integral components in modern optical microscopy, offering unparalleled flexibility and high magnification capabilities. These ...

Description: Reflective microscope objectives mark a significant leap in optical design, effectively addressing chromatic aberration and achieving diffraction-limited performance over a broad wavelength spectrum. ...

Description: Selecting the Right Optics for NIR Microscopy ...

Description: Delving into the realm of cutting-edge microscopy, the 50X long working distance objective lens emerges as a game-changer, offering unparalleled magnification for precise visualization in biomedical ...

Description: Our latest article explores how the confluence of AI and automation is revolutionizing widefield fluorescence image processing for academic and corporate labs. Learn how to leverage these ...

Description: Learn more about the key properties of cameras and how to use them to select the best camera for your microscopy application. ...

Description: This article gives a brief overview of how the combination of AI and automation can be used to empower academic and corporate labs to do more with less. ...

Description: Digital microscopes have revolutionized the world of microscopy, offering advanced and convenient features that make it easier than ever to capture, review, and share images of your samples. However, ...

Description: Bo Hyun Kim is a professor at the School of Mechanical Engineering, Soongsil University in South Korea. He is researching ultra-precision micromachining technology using digital microscopy and 3D ...

Description: Super-resolution (SR) microscopy is a broad category of recently developed methods in fluorescence-based light microscopy that have cleverly side-stepped the resolution limit imposed by diffraction on ...

Description: When choosing a motion control system, the software features and support that comes bundled with the hardware often plays a big role in the success of the project. ...

Description: In this article, we'll show you how to leverage the power of a motorized focus axis by using OpenCV to automatically discover a good position in fewer than 100 lines of Python code. ...

Description: Avantier's project introduces a custom-designed 25X objective lens for Isotope Ratio Mass Spectrometer systems, specifically tailored for researching isotopes. Operating on the principle of charged ...

Description: Avantier's small objective lens revolutionizes medical optical systems, particularly in dental health applications. This project focuses on utilizing a higher-resolution lens while reducing the ...

Description: This medical research project with Avantier employs a 20X objective lens to investigate human blood samples at the single-cell level, enabling detailed analysis of genetic expression, immune ...

Description: Immerse yourself into the transformative realm of optics with microstructure lens arrays-meticulously designed arrangements of nanoscale sub-lenses, each boasts an independent optical axis. In ...

Description: Get excited to delve into the revolutionary world of flow cytometry! This article breaks down the fundamental principles; from hydrodynamic focusing, to electronic detection. This versatile technique ...

Description: Fluorescence microscopy, vital in biomedical research, visualizes samples by exploiting fluorescence. It involves exciting molecules with a focused light source, often a laser, and capturing emitted ...

Description: To acquire a sharp image from a microscope, the sample has to be in focus. Learn how to leverage the power of a motorized focus axis by using OpenCV to automatically discover a good position in fewer ...

Description: Augmented reality can simplify complicated microscope-based manufacturing processes by overlaying text, images, videos, and measurements into the view seen from the eyepieces. ...

Description: Objective lenses are used in microscopy systems for a range of scientific research, industrial, and general lab applications. A microscope objective is typically composed of multiple lens elements and ...

Description: Nanometer precision was not really required when Intel developed their first microchips. The structure widths of the Intel 4004 processor back in 1971 were a generous 10 microns, or 1/100 of a ...

Description: 3D printing and additive manufacturing are gaining traction in prototyping and industrial manufacturing of complex parts. Typical 3D printers can produce feature sizes down to a few 10 microns. ...

Description: Homemade AFMs are low-cost and high-performance and provide flexibility and customization ...

Description: Fluorescent microscopy is especially useful for cytodiagnostics - the microscopic examination of cells in body tissue or fluids - and provides insights into fundamental research, for example, the ...

Description: PI explores the key principles of motion platforms in advanced microscopy ...

Description: Scanning laser confocal microscopy (SLCM) has become a popular inspection tool in both research laboratories and manufacturing production lines. With a 405 nm laser light source, SLCM combines ...

Description: The nondestructive testing (NDT) industry is experiencing an important technological advancement, as total focusing method (TFM) capable inspection devices are making their entry into market. The TFM ...

Description: If you’ve ever worked in a lab, you know an optical microscope uses an eyepiece and objective to magnify a small object. But as technology continues to advance, digital microscopes are ...

Description: Precise Sample Positioning is Crucial for Conclusive Images ...

Description: How to Combine Motorized Stages, Piezo Stages and Sample Holders ...

Description: Super-Resolution microscopy allows insights into intracellular processes and interactions at a molecular level. During the past two decades, advances in the field have led to significantly higher ...

Description: Fractography is an analytical technique used to determine the cause of fracturing in a metal structure. The method relies on the analysis of dimples and slips on the fracture's surface to determine ...

Description: Drill bits are widely used in industrial fields as a cutting tool. A drill bit is a thin spiral metal blade about 10 cm (3.9 in.) long. It is usually made of cemented carbide to resist wear and heat ...

Description: Semiconductors are manufactured using a precise process. One step is wire bonding, where electrodes on an integrated circuit are connected to lead frames using soldered gold, aluminum, and copper ...

Description: Integrated circuit (IC) manufacturing can be broken down into two processes-forming circuits on bare wafers and packaging. The circuit formation process begins with cylindrical pieces of semiconductor ...

Description: As an analytical technique, light microscopy provides unique insights across many areas of historical materials, from discovering an artifact's history to understanding the best course of action for ...

Description: Fluorescence microscopy is a ubiquitous and continuously evolving technique which permits one to peer into the biological world at the micron length scale and beyond, allowing direct access into the ...

Description: One of the factors that contributes to the recent considerable reduction in size and high integration of electronics and other devices is miniaturization of the electronic components that make them ...

Description: Electron microscopy allows investigations with extremely high lateral resolution down to a range of less than one nanometer. However, this places great demands on the imaging elements. And, of course, ...

Description: Very often individual classical microscopic methods are no longer sufficient in terms of optical resolution or information content. The combination of different microscopic methods yields more ...

Description: Atomic force microscopy (AFM) is used for surface measurements with resolution down to atomic levels - dimensions that are far beyond even the highest resolution optical microscopes. AFM is a ...

Description: High-Speed tracking of several particles allows measuring dynamic long-range interactions relevant to biotechnology and colloidal physics. In this paper we extend the successful technique of 3D ...

Description: The image quality of a two-photon microscope is often degraded by wavefront aberrations induced by the specimen. We demonstrate here that resolution and signal size in two-photon microcopy can be ...

Description: Red blood cells are amazingly deformable structures able to recover their initial shape even after large deformations as when passing through tight blood capillaries. The reason for this exceptional ...

Description: Metallography with Color and Contrast ...

Description: Orientation Imaging Microscopy OIM is a technique for characterizing the crystallographic orientation aspects of material microstructures. The technique is based on automated indexing of electron ...

Description: An EDAX Pegasus system with Orientation Imaging Microscopy (OIM™) was used to analyze an inclusion in a metallic sample. The matrix consisted primarily of Aluminum Titanium. Aluminum Oxide and ...

Description: Many five-fold branched Si particles (Sip) were observed in Al-40wt%Si functionally graded materials (FGMs) produced by a single step laser process on cast Al-alloy substrate (reference is made to our ...

Description: "Photonic applications using the II-Vi semiconductor Zinc Oxide (ZnO) are becoming increasingly prevalent, and research into even more uses is exploding, with hundreds of labs looking into the ...

Description: The refinement of the final microstructure is the main challenge of the thermomechanical processing of microalloyed steels. However, the final ferrite microstructure is the result of the combination ...

Description: OIM measurements were used to investigate the texture and microstructural gradients observed in extruded aluminium profiles. The material used in this study was an AlMgSi-alloy containing 0.45 wt% Mg ...

Description: As the features of integrated circuitry (IC) chips are scaled down to submicron dimensions, the manufacturer demands new technology to meet performance and reliability requirements for the electronic ...

Description: With relatively few progressions in conventional optical microscopy during the past decade, pushing through the physical limitations of these systems has proven to be challenging. Engineers have ...

Description: Prior Scientific, Inc. describes how automated positioning equipment is utilized in microspectrophotometry applications. ...

Description: Prior Scientific investigates how microscope positioning is utilized in imaging applications. ...

Description: Prior Scientific covers new positioning tools that are being utilized in the live-cell fluorescence fields. ...

Description: Compound microscopes differ from simple magnifiers in that there are two separate magnification steps that occur instead of one. The objective lens is nearest the subject under observation and ...