Plasma Source Mass Spectrometry: Applications and Emerging Technologies

Zo A. Quinn, Vladimir I. Baranov and Scott D. Tanner
MDS SCIEX, 71 Four Valley Drive, Concord, Ontario, Canada L4K 4V8
ICP-MS has been used for many biological applications in the past, including: the quantitation of toxic elements in blood and other body fluids; studying the transport and destiny of metals in vivo; monitoring the absorption and metabolism of both nutrient metals and metallo-drugs; characterizing metallo-proteins and metal homologues of amino acids and stable isotope tracing (uptake, metabolism, diagnostics). Typically in all these methods, the bio-molecules analyzed with the ICP-MS are already associated with a metal component. However...