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  • A Wave, Suspended: Follow-on Biologics
    procedures established for small molecules, human growth hormone, insulin, interleukins and interferons are available, as are versions of therapeutic proteins modified with polyethylene glycol (PEG) residues to improve pharmacokinetics.
  • Drug Delivery: The "Great Equalizer "
    ,? Haley observes. Perhaps the most prominent, technologically compelling example is PEGylation of proteins and peptides as practiced by Nektar Therapeutics (San Carlos, Calif.). Through PEGylation, polyethylene glycol residues are chemically attached to peptides and proteins to improve
  • A Wave, Suspended: Follow-on Biologics
    procedures established for small molecules, human growth hormone, insulin, interleukins and interferons are available, as are versions of therapeutic proteins modified with polyethylene glycol (PEG) residues to improve pharmacokinetics. Part of the challenge that FDA faces is the sheer complexity
  • Controlled Release Moves Beyond Patent Extension
    . Mechanical prolongation of drug release, although thus far dominating CR markets, is not the only strategy. Conjugation with polyethylene glycol (PEG; PEGylation ) has created immense value for developers of protein drugs. When attached to proteins or peptides, highly water-soluble PEG polymer

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