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  • Multi-Prong Infusion Needle Case Study
    Challenge: A medical device manufacturer needed to reduce the manufacturing cost of a multi-prong infusion needle used for tumor ablatement. The original design required the use of expensive Nitinol tubing, inflating the cost of the device due to the need for heat-set shaping to achieve
  • The Needle Gets Another Shot
    , says Matthias Poslovski, technical sales director for Inova and Kugler for the Optima Group Pharma. Disposable components, popular in upstream processing, have slowly migrated downstream to aid sterile manufacturing. Tubing, valves, containers, fill nozzles and filters for filling are all available
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    silicone tubing and filling needle. Once filing is completed, the tubing can be cleaned easily or disposed of. The filling unit is available in a range of sizes from stand-alone models for smaller facilities, to systems with up to 16 drives and filling needles controlled by one master control. Filling
  • A Tough Order to Fill
    equipment to fill syringes. With disposables, there is no product contact during filling, says Rosness. We use peristaltic tubing and the filling needles are all disposable. Cleaning validation goes away. Disposable filling is particularly beneficial for cytotoxic products., since
  • A Microfluidic System for Biological Particle Enrichment Using Contactless Dielectrophoresis
    . The degassed PDMS liquid. was then poured onto the silicon master and cured for 45 min. at 100 C (Fig. 1E). The solidified PDMS was removed from. the mold, and fluidic connections to the channels were. punched with 15-gauge blunt needles (Howard Electronic. Instruments, El Dorado, KS). Cleaned glass

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