Fundamental Concepts in the Design of Experiments, Fifth Edition

Chapter 13: Fractorial Replication

13.1 INTRODUCTION

As the number of factors to be considered in a factorial experiment increases, the number of treatment combinations increases very rapidly. This can be seen with a 2 f factorial where f = 5 requires 32 experiments for one replication, f = 6 requires 64, f = 7 requires 128, and so on. Along with this increase in the amount or experimentation comes an increase in the number of high-order interactions. Some of these high-order interactions may be used as error, since those above second order (three-way) would be difficult to explain if found significant. Table 13.1 gives some idea of the number of main effects, first-order, second-order, , interactions that can be recovered if a complete 2 f factorial can be run.

Table 13.1: Buildup of 2 f Factorial Effects

f

2 f

Main
Effect

Order of Interaction

1st

2nd

3rd

4th

5th

6th

7th

5

34

5

10

10

5

1

6

64

6

15

20

15

6

1

7

128

7

21

35

35

21

7

1

8

256

8

28

56

70

56

28

8

1

Considering f = 7, there will be 7 df for the seven main effects, 21 df for the 21 first-order interactions, and 35 df for the second-order interactions, leaving


for an error estimate, assuming no blocking and no interactions above second order. Even if this experiment were confounded in blocks, there is still a...

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