Mass Spectrometry: A Foundation Course

Appendix 7: Gas Phase Acidity Data

Acid M H

?H acid 0 (kJ mol)

MeC ?CH

1 589.31

MeOH

1 587.63

EtOH

1 574.66

HC ?CH

1 571.72

iPrOH

1 566.28

iBuOH

1 563.35

tBuOH

1 562.93

tBuCH 2O H

1 556.65

HF

1 555.40

PhCH 2O H

1 547.44

nPrOH

1 541.16

PhNH 2

1 536.97

CH 3SO 2CH 3

1 534.88

CH 3C HO

1 534.04

CF 3CH 2O H

1 525.67

pyrrole

1 510.18

MeSH

1 503.06

EtSH

1 496.36

nPrSH

1 492.17

tBuSH

1 485.06

H 2S

1 479.62

HCN

1 478.36

pMeOC 6H 4O H

1 472.50

CF 3C(=O)CH 3

1 466.64

PhOH

1 464.54

MeCO 2H

1 459.10

EtCO 2H

1 454.08

PhCO 2H

1418.49

HCl

1 408.86

CF 3CO 2H

1 351.08

(Data sourced from J.E. Bartmess and R.T. McIver Jr., The Gas Phase Acidity Scale, in Gas Phase Ion Chemistry, Vol. 2, Academic Press, New York, 1979. Data is derived from pulsed ICR measurements at 298 K and high pressure MS measurements (shaded) at 500 600 K)

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