Process Line / Continuous Particle Analyzers

Last Updated: April 1, 2025

Description

Process Line / Continuous Particle Analyzers are specialized instruments designed to continuously monitor and analyze the size and distribution of particles within a process stream. These analyzers provide real-time data on particle characteristics, which is crucial for maintaining product quality and optimizing process efficiency.

Working Principle

Process Line / Continuous Particle Analyzers operate using various techniques such as light scattering, diffraction, and attenuation. For instance, low-angle light laser scattering (LALLS) is a common method where a laser light source is used to illuminate particles, and the scattered light is measured to determine particle size and distribution. These analyzers are useful because they provide non-destructive and non-intrusive measurements, allowing for continuous monitoring without interrupting the process flow. This real-time data helps in maintaining consistent product quality and reducing waste.

Applications

These analyzers are widely used in industries where particle size and distribution are critical to the product's performance and quality. Specific examples include monitoring the particle size in pharmaceutical drug manufacturing to ensure proper dissolution rates and bioavailability, and in the paint industry to control pigment dispersion for consistent color and texture.

Advantages over other Particle Analyzers

Continuous Particle Analyzers offer several advantages over traditional batch or laboratory-based particle analysis methods. They provide real-time data, which allows for immediate adjustments to the process, enhancing productivity and reducing downtime. Unlike batch methods, they do not require sample extraction and preparation, which can introduce errors and delays.

Limitations

One limitation of Continuous Particle Analyzers is their potential sensitivity to environmental conditions such as vibration, which can affect the accuracy of measurements. Additionally, they may require specific calibration and maintenance to ensure consistent performance, which can be resource-intensive.

Considerations

When considering the implementation of a Continuous Particle Analyzer, it is important to evaluate the initial costs, which can be significant due to the complexity of the system. Operating expenses should also be considered, including the cost of maintenance personnel, calibration materials, and potential downtime for repairs. The durability and accuracy of the analyzer are crucial, as they directly impact the reliability of the data collected. Replacement and maintenance costs should be factored into the overall cost of ownership to ensure a comprehensive understanding of the investment required.

8 Results
Hand-Held Concentration Meter/ Counter -- 1506-9
from Terra Universal, Inc.

Lightweight and compact portability allows measuring in hard-to-reach areas. Reliable solid-state laser sensor provides a long, trouble-free service life. Isokinetic probe is built into processor housing. Two available models, with sensitivity ranges of 0.3 µm to 5 µm or 0.5 µm to... [See More]

  • Display & Special Features: Handheld; PC Interface / Networkable; Process Line Mounted for Continuous Monitoring; Video
  • Sample Type: Aerosol Droplets (Liquid in Gas)
  • Measurement Type: Count
  • Measuring Range: 0.3000 to ?
Inline Particle Probe -- Parsum IPP 50
from Malvern Instruments, Inc.

Malvern's newest sensor specifically designed to measure larger particles up to 2.5 mm in many processes including, chemicals and food products all types of granulates. [See More]

  • Display & Special Features: PC Interface / Networkable; Process Line Mounted for Continuous Monitoring; SPC
  • Sample Type: Aerosol Droplets (Liquid in Gas); Powder / Solid; Emulsion
  • Measurement Type: Size
  • Measuring Range: 50 to 2500
Nano Particle Size Analyzer -- SALD-7500nano
from Shimadzu Scientific Instruments, Inc.

A powerful new tool for research and development in nanotechnology and life sciences, and for measuring fine bubbles. Evaluation of the dispersion and aggregation characteristics of particles is realized with a wide measurement range and in real time. The SALD-7500nano was developed to provide... [See More]

  • Display & Special Features: Benchtop; PC Interface / Networkable; Process Line Mounted for Continuous Monitoring; Video
  • Sample Type: Emulsion
  • Measurement Type: Size
  • Measuring Range: 0.0070 to 800
Inline Particle Probe -- Parsum IPP 50-S
from Malvern Instruments, Inc.

Malvern's newest sensor specifically designed to measure larger particles in many processes dealing with granulates, such as the chemical and food product industries, among others. The sensor can be specifically modified to suit the process and material conditions by means of various accessories... [See More]

  • Display & Special Features: PC Interface / Networkable; Process Line Mounted for Continuous Monitoring; SPC
  • Sample Type: Aerosol Droplets (Liquid in Gas); Powder / Solid; Emulsion
  • Measurement Type: Size
  • Measuring Range: 50 to 2500
SALD-2300 Particle Size Analyzer -- SALD-2300
from Shimadzu Scientific Instruments, Inc.

The SALD-2300 multi-purpose analyzer provides continuous measurement in real time, at minimum one-second intervals, and has 21 CFR Part 11 compliant software as an option. It enables measurements of samples at a variety of concentrations without diluting or concentrating. In addition, the... [See More]

  • Display & Special Features: Benchtop; PC Interface / Networkable; Process Line Mounted for Continuous Monitoring; Video
  • Sample Type: Emulsion
  • Measurement Type: Size
  • Measuring Range: 0.0170 to 2500
Laser Diffraction System -- Insitec ALISS
from Malvern Instruments, Inc.

At-line particle size analyzer for dry processes. Ideal for use when centrally located among multiple mills. Rapid particle size analysis, based on laser diffraction, for particles in the size range 0.1 to 1000 µm. Fully automated analytical procedure, no sample preparation required. Easily... [See More]

  • Display & Special Features: Process Line Mounted for Continuous Monitoring; SPC; Video
  • Sample Type: Powder / Solid
  • Measurement Type: Size
  • Measuring Range: 0.5000 to 1000
SALD-3101 Laser Diffraction Particle Size Analyzer -- Model 3101
from Shimadzu Scientific Instruments, Inc.

The SALD-31010 is designed for measurement of coarse or dense particles with a variety of sampling options for both wet and dry samples. It seamlessly covers a wide measuring range from 0.05 to 3,000 µm using a single measurement principle, a single optical system, and a single light source. A... [See More]

  • Display & Special Features: Benchtop; PC Interface / Networkable; Process Line Mounted for Continuous Monitoring; SPC (optional feature)
  • Sample Type: Powder / Solid; Emulsion
  • Measurement Type: Size
  • Measuring Range: 0.0500 to 3000
Laser Diffraction System -- Insitec T
from Malvern Instruments, Inc.

The Insitec T particle size analyzer is designed to measure: Solid particulates suspended in gas process stream. Automatic on-line continuous, or at-line manual. Static installation. Real-time particle size analyzer based on laser diffraction 0.1 to 1000 µm. Designed for real-time control of... [See More]

  • Display & Special Features: PC Interface / Networkable; Process Line Mounted for Continuous Monitoring; SPC
  • Sample Type: Aerosol Droplets (Liquid in Gas)
  • Measurement Type: Size
  • Measuring Range: 0.5000 to 1000