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  • Synthesis of Magnetic, Fluorescent and Mesoporous Core-shell-structured Nanoparticles for Imaging, Targeting and Photodynamic Therapy
    A synthetic method to prepare novel multifunctional core-shell-structured mesoporous silica nanoparticles for simultaneous magnetic resonance (MR) and fluorescence imaging, cell targeting and photosensitization treatment has been developed. Superparamagnetic magnetite nanoparticles and fluorescent
  • A Comparison of Fluorescent Ca2+ Indicators for Imaging Local Ca2+ Signals in Cultured Cells
    Localized subcellular changes in Ca2+ serve as important cellular signaling elements, regulating processes as diverse as neuronal excitability and gene expression. Studies of cellular Ca2+ signaling have been greatly facilitated by the availability of fluorescent Ca2+ indicators. The respective
  • Utilizing Water Contact Angle to Predict Surface Preparedness for Dye Penetrant Application
    Reliably predicting dye penetrant wettability for fluorescent crack inspections hinges on understanding surface cleanliness prior to penetrant application. Validating the efficacy of a parts washer using water contact angle measurements is a non-destructive method for quantifying surface
  • Biological Research Using SWIR Camera Technology
    NIR-SWIR wavelengths have become important for biological research and clinical studies. Whether it is because of reduced light scattering at longer wavelengths, for detecting molecular (chemical) absorption bands or for capturing the emissions of multiple fluorescent dyes. Reduced scatter permits
  • the desired information. Some applications that use spectral filtering are: identifying places in a scene that have been marked with a fluorescent dye, by using a spectral filter in front of the camera that allows only light of the wavelength of the fluorescence to pass through the filter.
  • Red Enables Cell Membrane Study
    bilayers that mimic cell membranes. They wanted to create and image in vitro membrane models tagged with the fluorescent dye rhodamine. To capture the images, they needed a camera that not only has a high sensitivity to rhodamine's red light, but also offers the standard advantages of a CCD device.
  • Go Undercover
    Operational Excellence & Lean Six Sigma : measures invisible to humans or requiring special equipment for reading or detection, including water marks, inks and fluorescent dyes, as well as RFID and barcoding; or analytical: techniques, typically involving markers, that require sophisticated
  • Fast molecular tracking maps nanoscale dynamics of plasma membrane lipids
    We describe an optical method capable of tracking a single fluorescent molecule with a flexible choice of high spatial accuracy (~10-20 nm standard deviation or ~20-40 nm full-width-at-half-maximum) and temporal resolution (< 1 ms). The fluorescence signal during individual passages of fluorescent

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